Search results

Identifying and then successfully using drug X for disease Z is a conceptual insight. Much of what humans call 'reasoning' is 'guessing' based on necessarily flawed and incomplete data anyways?

I think hypoxanthine is relevant, but it's not easy to test reliably. Elevated values, I think might be a very strong indicator (but not a diagnostic biomarker due to a lack of specificity) for having ME.

What do you mean by 'necessarily'? I mean obviously it will not scale necessarily. The point is that we are very far from whatever the saturation point will be for what can maximally and safely be achieved through fundraising by patients and their loved ones. Furthermore, charities most often...

That's a bad reason for not campaigning for fundraising, imo. It's actually the worst of all reasons, because it's exactly those people that need funds raised the most. I am a very severe patient myself, so I fall in this group, at least from a physical capacity POV. I said twice not...

Who pressures anyone to do anything? How would this even be possible? Nobody has to do anything, obviously.

Lack of private funding is the main impediment to change for ME patients. The first thing that must happen to achieve that change is a shift in mindset, a vibe change needs to happen in the community. PwME, and maybe even more importantly their loved ones, need to understand that they can bring...

Hi everyone, I just wanted to say that whatever you’re doing or planning to do to get the information from S4ME out into the “real world,” I’m all for it. I think it’s so important to amplify the work being done here, and I’d love to support that. To help with this, I’d be happy to offer a...

So, funding is secured? Thank you!

They are looking for funding.

Can you say more about this? Where did you get this info from? I am specifically interested in the 'after resting' bit.

If your urine really is a dark brown (please google it for comparison) then that is essentially always an emergency. If it looks like Cola, you have to go to the hospital.

ME/CFS Review Inform ME(/CFS)

But aren't complement mediated events inflammatory?

I am pretty sure this is relevant. On the other hand, I would be somewhat surprised if this is specific to ME/CFS. The degree of dysregulation and of the resulting hypoxia might be somewhat specific, though? This research needs replication, but the results should hardly surprise anyone. If...

Thank you, Chris. What is the situation in regards to funding? I am not sure what is the situation post Brexit, but could you apply for EU funding for this project? I vaguely remember reading something about how Starmer (?) wants to reestablish eligibility for UK based projects for HORIZON...

ME patients can't utilize sugar and fats normally, are we surprised to find 'insuline resistance?' If you eat sugar, and your cells can't utilise it (for potentially a whole bunch of reasons) your BS will rise. Increased BS doesn't automatically indicate IR though, it also doesn't help that IR...

Thank you for your insights. A few follow-up questions came to mind: 1. Are there specific methods or approaches to test your hypothesis? 2. How does the hyperadrenergic form of POTS integrate into your model? Specifically, considering that hyperadrenergic POTS is characterized by elevated...

If the results are real, you were wrong about “all that pseudoscience” that led them there, I guess.

Absolutely, the CF community fundraised billions of dollars privately to get there. There are no miracles.

I think you talked about ‘very delayed PEM’ before, but can’t find it, what is that to you? Thank you!