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https://sciencedaily.com/releases/2025/11/251102205009.htm "The researchers studied bacteria that carry extremely old, inactive viruses and found that these dormant invaders still play a protective role." Maybe our cells have these too. Isn't a lot of our DNA old viral fragments? More...

Our gut is full of all sorts of phages, so wouldn't the rest of our body be too? Our gut immune cells apparently grab bacteria (and maybe other microbes?) and drag them to our (was it thymus?) glands to teach new cells to ignore them. "Hey class: meet G45d565treew55yu. He's a good guy!" So...

Does this synapse damage theory fit the observed effects? Would that theory cause effects that aren't observed (loss of specific memories, for example)?

I claim ME brain. Too much effort to picture how it was normally written.

I keep suggesting testing muscle performance with electrical stimulation, bypassing neural factors.

Not completely, since as others pointed out, viruses can hide in tissue and not show up in blood. If a study on all those potential hiding places turn up negative, the researchers who are invested in the persistent virus theory can maybe claim that the viruses only reveal their true nature...

There's also 5/3 samples of water with viruses detected. Should we jump to any conclusions about that? Statistical data from small studies doesn't have much weight.

"Participants were asked, “Have you ever been told by a doctor or other health professional that you had CFS or ME?”" Fine, toss that study directly into the wastebin. They're basing their study on doctor's decision about a disease they are uneducated about. I guess they're simply assuming...

That's targeting the symptoms, rather than the disease. I've had my ME switch completely off from at least 3 different chemicals (prednisone, T2, cuminaldehyde). So, in my experience it's not difficult to target the disease; it's difficult to maintain the off state, or to maintain whatever...

I agree with that. I didn't wear a seatbelt because I was worried about crashing (rare event); it was because I didn't want to get pulled over and fined (much more likely event). I encountered several "checking belt usage" police stops. Since this thread is about the value of a letter to the...

I don't know if my case was unique or just exaggerated, but the form of exercise--how much muscles were pushed beyond their normal movement--was the main factor in triggering PEM. A few seconds of unaccustomed muscle usage was far more likely to trigger PEM than hours of strenuous accustomed...

Sure, and you can drop it to nearly zero ... at ridiculous cost. What I was suggesting was a study with the intended audience of hospital administrators, showing the overall effect on the annual budget of requiring masks for specific tasks (or requiring aprons for toilet-cleaning). We don't...

Two significant issues I hadn't thought of. Hard to calculate the psychological costs to patients by covering faces. For a greatly exaggerated example, imagine how you'd feel as a patient if all the staff wore WWII gasmasks. Definitely hard to hear what they'd be saying. Do masks for...

Since "brain fog" is unmeasurable and not clearly defined, practically everything other than perfect mental clarity can fit that term. Is chemotherapy BFthe same as ME BF? Maybe there's someone who has had chemotherapy BF and ME BF and can give an opinion, although suffering from BF isn't the...

Well, at present there isn't any alternative to targeting multiple symptoms, since there is no treatment that reliably targets the disease. For that matter, there's no reliable treatment for any of the symptoms. Not safe ones, since I'm guessing that opioids are reliable at treating chronic...

Given that hospital's hygiene practices, what would the result of a government "recommendation" for N95 masks to be worn at all times? If it's not enforced, it won't be followed. If it is enforced and not supported by additional funding, hygiene might be cut further in other areas. I'm not...

Oh well, it was worth mentioning. For theorizing, more information is better than no information. Maybe we should have a sub-forum for researchers to ask for specific patient experiences, such as "Have you tried drug x and what effect did it have on this symptom?"

I doubt it will be spread evenly. Most might go to a few diseases that get some attention because a celebrity has it, or some other reason for being "the latest fad". The claims for being generous towards rare diseases will likely be spread evenly.

Okay, so allow 6 hrs before your next dozen tablets. I'll try to keep that in mind. Of course, since I already have bad tinnitus, would I notice? Avoiding aspirin for several years now hasn't reduced it. On to the next heath scare!

It's a matter of numbers. You probably can't reduce it to 0.00000%. Also, the countermeasures, whether it's respirators or intense UV illumination or whatever, likely has a non-zero chance of harm. The countermeasures also have a dollar cost, which means less money available for other...