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    Amanita muscaria extract potentiates production of proinflammatory cytokines by dsRNA-activated human microglia 2023, Wagner et al

    Discussion of Tamura et al: https://www.s4me.info/threads/animal-models-for-neuroinflammation-and-potential-treatment-methods-2022-tamura-et-al.28604/ Amanita muscaria or Fly Agaric is a beautiful but toxic fungal fruiting body with reputed psychoactive effects. Psyched Wellness reveals...
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    How many people die from snakebites?

    Saloni Dattani Substack How many people die from snakebites? https://salonium.substack.com/p/14-how-many-people-die-from-snakebites Study: Trends in snakebite deaths in India from 2000 to 2019 in a nationally representative mortality study (Suraweera et al., 2020) Here’s a statistic that...
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    Reduced MC4R signaling alters nociceptive thresholds associated with red hair, 2021, Robinson et al

    Of interest because it demonstrates the potential for small genetic variation to have subtle impacts on function.
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    Reduced MC4R signaling alters nociceptive thresholds associated with red hair, 2021, Robinson et al

    Reduced MC4R signaling alters nociceptive thresholds associated with red hair Kathleen C. Robinson, Lajos V. Kemény, Gillian L. Fell, Andrea L. Hermann, Jennifer Allouche , Weihua Ding, Ajay Yekkirala, Jennifer J. Hsiao, Mack Y. Su, Nicholas Theodosakis , Gabor Kozak , Yuichi Takeuchi, Shiqian...
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    Prevalence and predictors of long COVID among non-hospitalised adolescents and young adults: a prospective controlled cohort study, 2022, Wyller et al

    Flocking/shoaling ? Grants and data are the attractants and the group behaviour based on instinctive following of a small number of individuals, ultimately leading to circular citing and mutual congratulations on coming to the same conclusion because that's where their collective limited...
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    SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients, 2023, Charvet et al.

    "Affiliations GeNeuro Innovation" https://www.geneuro.com/en/technologies/rationale "Stopping the progression of autoimmune diseases GeNeuro is pursuing a novel approach for treating autoimmune diseases by seeking to block mechanisms suspected of participating to their onset and development...
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    Catalogue of Bias

    Catalogue of Bias About Bias enters health studies at all stages and often influences the magnitude and direction of results. To obtain the least biased information, researchers must acknowledge the potential presence of biases and take steps to avoid and minimise their effects. Equally, in...
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    Poll: Who will find the answer to ME: Humans or AI?

    The answer is 42 - yes but what is the question ? There a profound problems of interpretability* in AI and it's very difficult to make sound progress if you can't demonstrate how the solution was arrived at. And that's even without the challenge of heterogeneity in ME/CFS - is it a single...
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    The biology of coronavirus COVID-19 - including research and treatments

    If the market wasn't the source of COVID 19, it nevertheless constituted a serious ongoing public health threat for the spread of known and novel zoonoses. (my bolding) "The HSM is located in the Jianghan District in the downtown area of Wuhan, the capital city of Hubei Province, and is...
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    UK: Disability benefits (UC, ESA and PIP) - news and updates 2023 (including government plans to scrap the work capability assessment)

    Benefit sanctions statistics to October 2022 (experimental) "This is the latest quarterly release of statistics on Benefit Sanctions and includes data up to October 2022. Statistics covered in this bulletin include data for sanction decisions during the coronavirus (COVID-19) pandemic...
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    Post-COVID-19 condition and persisting symptoms in English schoolchildren: repeated surveys to March 2022 2023 Warren-Gash et al

    Authors are all statisticians (ONS) or epidemiologists so I'm not sure there is an obvious pro psych agenda. There are limitations on cohort selection and classification - the cohort results from a monitoring programme set up as an early response to the pandemic essentially as a public health...
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    PASCLex: A comprehensive post-acute sequelae of COVID-19 (PASC) symptom lexicon derived from electronic health record clinical notes, 2022, Liqin e/a

    Journal of Biomedical Informatics PASCLex: A comprehensive post-acute sequelae of COVID-19 (PASC) symptom lexicon derived from electronic health record clinical notes Liqin Wang, Dinah Foer, Erin MacPhaul, Ying-Chih Lo, David W. Bates, Li Zhou Abstract Objective To develop a comprehensive...
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    Has the arrival of Long Covid strengthened or weakened the influence of psychosomatic medicine? Discussion thread

    Has the arrival of Long Covid strengthened or weakened the influence of psychosomatic medicine ? There's a lot to unpack in that question, a many to many problem of systems analysis. Long Covid isn't one thing - as a label it's a short hand for a raft of consequences of being infected by a...
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    UK: Disability benefits (UC, ESA and PIP) - news and updates 2023 (including government plans to scrap the work capability assessment)

    This "trap" was explicitly part of the (Lord) Freud reforms of 2010 onward, I can't find the quote but the Secretary of State (IDS ?) stated clearly in an interview that GP letters were to be downgraded and only reports from Specialists would be considered to have primary value in evidence. The...
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    One of the world’s most cited scientists, Rafael Luque, suspended without pay for 13 years, 2023, Manuel Ansede

    El Pais One of the most cited scientists in the world, the Spanish chemist Rafael Luque, has been suspended without pay for the next 13 years, according to Luque himself and the institution where he worked until recently, the University of Córdoba in Spain. The university has sanctioned Luque...
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    UK: Disability benefits (UC, ESA and PIP) - news and updates 2023 (including government plans to scrap the work capability assessment)

    DWP PIP warning as thousands of benefit claimants have their payments stopped Thousands have lost their disability benefit because of issues over returning their review forms, the Department of Work and Pensions (DWP) has revealed. As our colleagues at Chronicle Live report, Up to 42,000...
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    UK: Disability benefits (UC, ESA and PIP) - news and updates 2023 (including government plans to scrap the work capability assessment)

    It would be an advance if the decision makers (the DWP employees who are charged with collating the evidence and rendering or refusing an award) were to accord to the letter of the law, it would reduce the number of unnecessary appeals - currently about 1 in 20 decisions are appealed of which...
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    NHS Hormone Replacement Therapy Prescription Prepayment Certificate (HRT PPC)

    Also: https://www.gov.uk/government/news/new-scheme-for-cheaper-hormone-replacement-therapy-launches - Prescription charges only apply in England.
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    UK: Disability benefits (UC, ESA and PIP) - news and updates 2023 (including government plans to scrap the work capability assessment)

    Diagnosis has not served as a substantial weighting factor in awarding UK disability/sickness benefits - the focus even back in the days of the Invalidity Pension was on degree of incapacity as identified by test/assessment, although support of GP and or Specialist did have some weight. For...
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    10 easy ways to reduce your fatigue fast! Times article about Katrina Antram

    About the author: Karina Antram Karina Antram (BSc hons, DIP-NT) is a registered nutritionist and graduate of the renowned College of Naturopathic Medicine and an executive coach. Karina is hugely passionate about health and wellbeing after her own health struggle. Linked-in: Founder of NOCO...
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