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  1. Evergreen

    Grip test results and brain imaging in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    He got his own back later in the assessment by jamming my head into my neck. But I had made my point!
  2. Evergreen

    Grip test results and brain imaging in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Most of Jäkel's were post-infectious like Walitt's: 52/61 females and 40/44 males. That's 87.6%.
  3. Evergreen

    Grip test results and brain imaging in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Crossposted with you Utsikt! Takes me ages to put a post together.
  4. Evergreen

    Grip test results and brain imaging in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Good call, Trish. I've been too wrecked to look too closely at baseline characteristics which are likely the answer. Duration of illhness In Jäkel's study, mean duration of illness for both females and males was 4 years, but with a wide range: 1-32 years for females and 1-42 years for males...
  5. Evergreen

    Grip test results and brain imaging in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    I can't find any info in Walitt et al. 2024 about exactly how they measured it. But I think maximum voluntary contraction is pretty standard. It's the flipped results I can't get my head around - if Jäkel's subjects had the same sex composition as Walitt's (59% female), then the mean max hand...
  6. Evergreen

    Grip test results and brain imaging in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Can anyone help me make sense of this? Walitt et al. 2024 reported higher max hand grip than Jäkel et al. 2021 despite lower physical function scores. Mean max hand grip of people with ME/CFS In Jäkel et al. 2021, the mean max hand grip in kg for females with ME/CFS was 18.1 and 31.2 for...
  7. Evergreen

    Variation in Repeated Handgrip Strength Testing Indicates Submaximal Force Production in Patients With [ME/CFS], 2025, Popkirov

    Excellent debunking. Will you write a letter to the journal? Letters to the Editor: max. 500 words, including a maximum of five references. Letters express views about articles published in EJoN or present ideas or findings of scientific interest that do not constitute original research...
  8. Evergreen

    Variation in Repeated Handgrip Strength Testing Indicates Submaximal Force Production in Patients With [ME/CFS], 2025, Popkirov

    Oh good, I couldn't understand it so I'll come back later after a rest!
  9. Evergreen

    Variation in Repeated Handgrip Strength Testing Indicates Submaximal Force Production in Patients With [ME/CFS], 2025, Popkirov

    Indeed. The difference disappears for males but not females when they account for peripheral fatigue. This excludes nearly half of the females and males with ME/CFS from the second analysis on the following basis: If the half that were included in the second analysis had significantly...
  10. Evergreen

    Variation in Repeated Handgrip Strength Testing Indicates Submaximal Force Production in Patients With [ME/CFS], 2025, Popkirov

    Who said it was a neutral discussion of the evidence? Agree, that's why I called it out above.
  11. Evergreen

    Variation in Repeated Handgrip Strength Testing Indicates Submaximal Force Production in Patients With [ME/CFS], 2025, Popkirov

    Maybe. My point is not that he has reached a good understanding, but that in the discussion he gives the question a lot more thought than any other neurologist in the FND camp ever has (in writing). It's a very lengthy discussion for a very simple post-hoc analysis. He's as limited by bias...
  12. Evergreen

    Variation in Repeated Handgrip Strength Testing Indicates Submaximal Force Production in Patients With [ME/CFS], 2025, Popkirov

    Essentially, yes. My PEM was not in the form of crashes at the time. Instead, I would just feel worse. And that did not happen, until it did, by which time it was too late. Not necessarily. At the time, I did not. Now, I think it's possible, and there are a few reasons why I think it's...
  13. Evergreen

    Variation in Repeated Handgrip Strength Testing Indicates Submaximal Force Production in Patients With [ME/CFS], 2025, Popkirov

    It's just so frustrating to see someone who is really trying to understand what is going on here, land again at what is essentially GET and CBT as the recommendation. He appeals to the well-worn argument that it's poorly implemented GET that is the problem. The author writes: 38 is Kindlon's...
  14. Evergreen

    Age-Related Changes in the Clinical Picture of Long COVID, 2025, Fain, Hornig et al

    Is it just me or is the title and framing off? They didn't look at "age-related changes", they looked at "age-related differences". They didn't look at the "impact of aging", they looked at the impact of "age". To look at the impact of aging they'd have to follow people over time and see what...
  15. Evergreen

    ‘You’re alive, but are you living?’ Exploring long COVID impact on social and leisure well-being for individuals and caregivers, 2025, Leighton et al

    Well, the evidence from ME/CFS rehab at NHS specialist clinics suggests they'll be disappointed, if the people with LC they're trying to rehabilitate have ME/CFS: Collin & Crawley 2017 found that approximately 1 year after patients treated 2014-2016 started attending a specialist clinic...
  16. Evergreen

    Using Compression Stockings to Prevent Recurrence of Vasovagal Syncope, 2025, Tavolinejad

    I'm selfishly glad to see these results, because I tried compression stockings and couldn't tolerate them for an unexpected reason - they do not play nice with Haglund's deformity (think heels that don't like being squeezed). I tried everything for 3 months - wore cushioned sports sock...
  17. Evergreen

    What to you think caused your ME/CFS, and what do you think has helped?

    To explain what I mean, something a bit like Jason et al. described here in their prospective study of students who got glandular fever and did or did not develop ME/CFS:
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