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The Effects of a Mindfulness-Based Intervention on Depression and Anxiety in the Long-COVID Population Long-COVID is a complicated, post-viral syndrome involving multiple body systems and can present with neuropsychiatric symptoms. Little has been reported about the neuropsychiatric symptoms...

Systrom — Mitochondrial biomass is down in all. (This is opposite to genetic primary mitochondrial myopathies where biomass increases to compensate.) Then you have two subsets: high systemic O2 extractors and low systemic O2 extractors (at peak exercise). Predicated on unimpaired or impaired...

Re: the rubber hand illusion. Yes, apparently also octopuses (octopodes for the pedants). Rubber arm illusion in octopus (2025, Current Biology) Commentary in Science: Octopuses fall for the ‘rubber arm’ illusion, just like us

Assessment of retinal vasoreactivity to hyperoxia as a microvascular biomarker using optical coherence tomography angiography Ruyi Zhai; Xiangmei Kong; Gezhi Xu CLINICAL RELEVANCE A substantial proportion of mild coronavirus disease 2019 survivors exhibit persistent systemic manifestations...

Some comments on the Pulse article —

Some summary quotes — A few of their references — Skull bone marrow and skull meninges channels: redefining the landscape of central nervous system immune surveillance (2025, Nature Cell Death & Disease) Skull bone marrow channels as immune gateways to the central nervous system (2023...

Clip courtesy of Broken Battery. (Not a great intro by one of the Breakfast team - "Tired all the time, poor sleep and brain fog")

Evidence for a role of skull bone marrow in human chronic pain as revealed by TSPO PET imaging The skull bone marrow is emerging as a critical hub for neuroimmune signaling in various disorders, with the potential to reshape how we understand brain-immune interactions. However, its role in...

‘Most People with Long COVID Are Their Own Doctors’: Self-Tracking and Online Patient Groups as Pathways to Challenging Epistemic Injustice Sazana Jayadeva; Deborah Lupton This article focuses on the struggles of people with Long COVID to obtain diagnoses and treatment in the face of medical...

Endoplasmic Reticulum Stress Amplifies Cytokine Responses in Astrocytes via a PERK/eIF2α/JAK1 Signaling Axis Aberrant activation of multiple cellular processes and signaling pathways is a hallmark of many neurological disorders. Understanding how these processes interact is crucial for...

Persistence of fatigue in the absence of pathophysiological mechanisms in some patients more than 2 years after the original SARS-CoV-2 infection Following an acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a substantial percentage of patients report the...

"To Infinity and Beyond…" :banghead: Does not reference eg [Interventions for the management of long covid post-covid condition: living systematic review](https://doi.org/10.1136/bmj-2024-081318) (2024) although preceded its publication.

Comparison of telemedicine-assisted psychotherapy, exercise therapy, or a combination of both in patients with post-COVID-19 syndrome TelPoCo: study protocol for a randomized controlled trial Post-COVID-19 syndrome (PCS) presents in a multitude of ways, with fatigue, physical constraints, and...

He even signs that post off with "#pvs" so he himself seems to have thought it was just postviral fatigue syndrome.

GeneCards — SST FKBP5 ELFN1 MAD1L1 KCNIP4

Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD Hwang, Ahyeon; Skarica, Mario; Xu, Siwei; Coudriet, Jensine; Lee, Che Yu; Lin, Lin; Terwilliger, Rosemarie; Sliby, Alexa-Nicole; Wang, Jiawei; Nguyen, Tuan; Li, Hongyu; Wu, Min; Dai, Yi; Duan, Ziheng; Srinivasan...

Leveraging A Randomized Trial to Assess Relationships between Transeptal Puncture, Brain Emboli, and Migraine Symptoms Elias; Tung; Gerstenfeld; Hue; Lin; Cheng; Weiss; Tzou; Hsia; Ehdaie; Cooper; Bunch; Arkles; Nazer; Lee; Hadjis; Nguyen; Chelu; Moss; Hsu; Marcus BACKGROUND Catheter ablation...

Reddit thread in the Long Haulers' group: Anybody else get told it’s “Functional Neurological Disorder” (FND) ? Including this comment, which quotes a neurologist's discussion with the patient — In case anyone was wondering what the practical "thinking" is at the coal-face. Counterpoint...