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Wow, Fightback4Justice look really good. I like the team photos on the website, which convey a sense that they know what they are doing, and are enthusiastic to help. I am going to contact them. Thank you very much ladycatlover.

I don't know; it may just be a quirk of the influenzavirus subtype and viral genetic makeup that determines whether it can cross the blood-brain barrier. There are dozens of subtypes, so you'd have to test them all to see if there's any trend. It's interesting that during the 1957...

Would you know who the best experts are for ESA? Is it a Citizen's Advice bureau, local job centre, unemployment benefits office? My postcode area also has the new Universal Credit fully rolled out, which I understand will eventually replace ESA, so that's another option (which only further...

Thanks for pointing that out. It does say in that link though that to get the 'New style' ESA or the contribution-based ESA you need to have been working and paid National Insurance contributions in the last 2 to 3 years. So I don't think those apply to people who have not been able to work for...

Interesting in that article how influenzavirus H1N1 (swine flu) was not able to cross the blood-brain barrier and infect the brain, but influenzavirus H5N1 (bird flu) was able to.

Thanks very much Estherbot, that's a nice summary and a useful link. It's interesting that in the link in the section "Ill, disabled or on sick pay" it says that you can get contributions (NICs) to your pension paid for, even if you are not on ESA but qualify for ESA (by these eligibility...

Ah right, well I did not even know that! I thought PIP was the main disability support provider. Shows how little I know! Thanks Esther. So if I want to try to for disability support, Employment and Support Allowance (ESA) would normally be the first port of call? I'm mid-50s now, so it's...

I agree that if you are talking about phase III clinical trials, sure, we don't have that kind of evidence for these treatments. And the benefits these treatments provide are often not dramatic, so they don't attract a great deal of interest in terms of large clinical studies. But some on the...

I developed ME/CFS as well as a whole set of mental health symptoms (depression, severe anhedonia, moderate to severe generalized anxiety disorder, and some mild psychosis on some days), as well as severe ADHD after a viral brain infection I had in 2005. This brain infection also caused some...

How many drugs and supplements out of the following fairly standard list of medications known to help ME/CFS have you tried? Many of these are employed by leading ME/CFS doctors. B12 methylcobalamin injections Low-dose naltrexone Oxymatrine (for enterovirus ME/CFS) Valcyte (for herpesvirus...

Yes, I believe the effect of angiotensin receptor blockers (ARBs) like Benicar on the VDR has not been demonstrated empirically, but only in silico studies involving computer modeling of the molecular interactions of ARB drugs and the vitamin D receptor, done by Marshall and colleagues. I don't...

That makes more sense. From memory, I thought Benford's law would always apply when you have a normal distribution, but maybe I got that wrong (it was decades ago that I read about Benford's law).

Sure, but when the data falls into a normal distribution, which a lot of real-life data does, then Benford's law applies. Of course if you are a dodgy accountant who knows about Benford's law, then you can actually generate fake data (ie, have 30% of numbers start with 1) which will pass the...

When I saw the title of this thread, it brought to mind the fascinating Benford's law, which states that in any genuine set of data, if you count up all the numbers, you should find around 30% of those numbers being with a "1", and not around 11% as you might expect. However, in a fake set of...

In the Marshall Protocol, you are taking the drug Benicar which activates the vitamin D receptor (VDR), so as I understand it, even if your vitamin D levels are low, you will still have VDR activation from Benicar. The overall idea of the Marshall Protocol is not to reduce VDR activation, but...

My guess is that its effects will probably be minor, and I would not spend $400 for just some minor improvements. It's possible though that people with severe POTS might get more benefit. We will have to await reports of patients using it.

If were $20 rather than $400 I perhaps would not mind trying it, to see if it might help my POTS a bit. I can't imagine it will have any dramatic benefits though. At the moment my strategy for ameliorating POTS while seated is to sit semi-cross legged, in a semi-yoga lotus pose. I am too...

I've never come across any instance where Cort has sold anything on his site, or through his blog articles (apart from some Amazon affiliate links on the site, and a donations scheme — which this forum also has). So I am not sure why you say Cort hawks everything. There is a difference between...

I also found this recent paper on the discovery of probable enterovirus particles in the brainstem neurons of Parkinson's patients very interesting. The study used an electron microscope to observe virus-like particles of diameter ~30 nm within the neurons — which is the diameter of enterovirus...

That's what the authors said. Silicone is an immune modulator, used in some vaccines as an adjuvant. So possibly silicone implants might trigger ME/CFS in a way similar to the reported vaccine-triggered ME/CFS cases?