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Well, let's be real here, how the fudge would they possibly know there is something to look at? Oh, right, we gotta figure it out first and tell them about it because no one is randomly checking... brain natriuthingy peptides? What actually fits the timeframe? I feel like shit for a day before...

I only got the minor thing where muscle fatigue could actually be in part responsible for the brain fatigue. IIRC, if muscles are 'stuck' in a position too long or cut off from sufficient blood supply for some other reason they can start to send pain signals (relaxing muscles takes energy as...

SO glad you brought that up, because if we wanna be really rigorous about it we need to establish what our non-crash baseline from which we are operating from is to discern if we are just wobbling around on 3 (or potentially more) paths to crashness to varying degrees or if they are more or less...

In our defense though, it is actually genuinely hard to take note with precision of what is going on because of overlap and then there is another layer because there sometimes are no words for what we feel, what we feel and notice may not be the most important thing to talk about, and the words...

Seems like a good idea in general. If someone really wants to go for stuff like this I don't see why they couldn't do so in private practice. I would have liked it if the focus was less on the inherent dangers of those therapies - which seem to be pretty low - and it was worded more clearly that...

There must be some truth to this, don't judge! I've had (in retrospect) a remarkably uneventful magical carefree life until I caught mono. Afterwards everything was suddenly unbelievably hard. This is an event from my past that was pretty stressful to deal with I guess. I fully accept that this...

Plot twist would be if fake psychs were on average actually genuinely helpful for patients because they didn't undergo traditional training and just applied common sense and looked up meds on wikipedia between appointments. Because the few I have seen very evidently didn't do either of those...

It may be a bit weird but the one that makes me raise ye olde eyebrow is... mistletoe therapy? I'm also really keen to hear what they can tell me that helps my financial situation. No, really, please, do tell.

I think the point is that one could easily use it as an objective outcome measure and if there is no beneficial change, it will be noticeable. If an intervention does nothing, this test should show it unless it turns out to be unreliable in some way (due to random fluctuations when tested on...

If this turns out to be reliable it should be really easy to do and not trigger significant worsening afterwards... I'd be interested to see how grip strength varies over months on different days and whether this can be tied to the muscles themselves or something neurological. We usually only...

Yup, everytime I have a normal flu or common cold (which is relatively rare as I don't get out that much anymore) my ME symptoms back off a lot. It's like a vacation. A vacation during which you have the flu, sure, but I can read way more, do more around the house, move around more easily...

This is something I would wish was more widely accepted as being so abundantly obvious that it never needs to be said again ever. I do not understand the entire division between 'naturopathic' and 'allopathic' and other types of medicine - stuff either works or doesn't, and you either know about...

Didn't bother to read more than the excerpt you posted, but the general premise is flawed the way it is depicted because a) More exercise than you can handle will decrease fitness transiently because you will be forced to take a break (higher susceptibility to just the common cold etc is a topic...

I agree. The way the reuters article is written is... 'interesting'. It is like they just asked Blakemore or someone like him for his opinion in order to give him some space to either protect his vested interests or blatantly misrepresent the situation for some other reason. It should be...

So this would imply that the fact that you understood how to interpret science in a technically correct way was seen as enough of a 'conflict of interest' to not allow you to take part here? Did I miss something? This is literally not what the term 'CoI' means.

Not to be a cynic, but if they intend to 'allow [...] time to adequately address the feedback', who decides what is adequate here? Without an actual scientist from the real world overseeing this process I would not be surprised if they just added some BS sentence to the tune of 'while some...

This is the exact opposite of my experience. High intensity short duration is borderline manageable sometimes, while anything longer duration completely wrecks me for weeks. Which makes sense as aerobic energy production seems to be what is impaired in us for whatever reason. It feels a bit like...

This may merit a whole thread of its own, but let's see how far we get here: Why is that, actually? I may be wrong here but as far as I know research grants are not necessarily given out for specific diseases - or at least not exclusively - and I would imagine that there must be some people...

I just wanted to ask this very question as well. I vaguely remember reading something about how an increase in IDO is necessary for the maternal immune system to not attack the fetus, and blocking it with 1-methyl-tryptophan leads to a t-cell mediated attack on the fetal tissue. There must be...

I think it does the same thing to me, it just takes 15-30 minutes to swing back the other way around and suddenly the brainfog lifts for a while! I can't get out initially anyway, but either I am big enough or our tub is small enough so I don't have drowning issues... I don't really want to...