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Just remember, Dapsone comes with potential baggage. I seem to recall Hemolytic anemia possibly being one, for example. H suggests limiting treatment duration to,hmm, I don't remember. But not long. It's been my experience (personal and relayed) that some clinicians shrug off those constraints...

One thing I've learned over way too long is that research-smarts is not necessarily the same as clinical-smarts. In many ways they are cross-elastic and overlap. Sometimes, however, they can be divorced from one another. I love reading the research, but I often take findings with a grain of...

Antibody titre, off and on. Most of the time I test negative. I can usually anticipate a flare as I test positive for hemolyitic anemia just before I do. I've tested microti-positive through Mayo and the NIH, so, eh, pretty good facilities. Treatment? Yes, I cannot remember what I took, though...

Don't think TBE is in the US. But these symptoms noted in the article could - I'd think - ring a bell with many in this forum. Unlike the 3 B's, TBE is caused by a virus.

If you test positive for duncani then you're automatically excluded. Check out exclusions. One is if patient is infected with any other tick-borne disease.

Speaking of long term TBD sequelae, do these symptoms after Tick-Borne-Encephalitis strike a cord...

Both b duncani and microti may run chronic, at least as far as I can deduce. There is some positive news purportedly for sufferers of long term b microti, but even then, you'll probably know treatment recommendations are a minimum of six weeks, and that with a tier 3 drug, and no guarantees...

Most people have no idea...

How could they not get 24 Lyme patients when Columbia is literally surrounded by areas that can be characterized not merely as Lyme endemic, but arguably Lyme epidemic? You've Connecticut to the northeast, Long Island to the east. New Jersey and PA to the west. Puzzling.

As an aside, but uncomfortably related matter: My wife just got a new pacemaker defibrillator. It comes with a wifi monitoring device that somewhat resembles Amazon's Alexa. She was told to leave it on 24/7 so they could always have her monitored. She protested on invasion of privacy grounds...

Well, not just incompetence and dysfunction. I'd add greed and legacy concerns and govt interests and laziness and corruption.

Sometimes I think medicine is etch-a-sketch art. You can create whatever picture suites you at any given moment, then erase and start over with an altogether different picture. If history stands for anything, I suspect that is what will happen with LC. Once the pandemic is truly in the rear...

I must admit I am not up on my Covid research. But if Covid is potentially securing priviledged sites in tissue, and it cannot easily be found in serum, short of biopsies (hit or miss since we've no way of knowing yet what preferred tissue might be), or autopsies (these days far from a given)...

"We anticipate that the most common sequelae to COVID-19 will be a postviral fatiguing syndrome and its persistent mix of somatic and psychiatric complaints in the absence of a clearly observable cause." Small wonder. What do they mean "in the absence of a clearly observable cause?" I was...

Seems to me there is an argument to be made for a correlate, a cognitive one. TEMMA: The Theory of Effort Minimization in Mental Activity. If there were, I would subscribe to it. I do my best to minimize concentration, strong emotions, math, judgement...I do not mean this ironically. I pay a...

Welcome, @5vforest ! I think Fallon's NIH excursion was slated to wrap up early this Spring. I'm not sure if covid has caused delays. The good news is it's a structured study. Bad news is I think it's on the small size, like 24 or so patients. With an annual infection count in the US alone...

Not sure about his talk, but technically the slide in question does not say EBV or SARS etc cause ME/CFS. It says x % of patients infected with those develop ME/CFS symptoms. Also, Chia is part of one of those research teams; it's a stretch to think Lipkin would be unaware of his efforts, but I...

I did not listen to the presentations, so perhaps it's folded into those, but I could not find anything definitive in terms of cohorts' distribution through the US. My sense, based on the slides, is that a majority are from within the US, and of those, most come from the NorthEast/MidAtlantic...

I was just being silly. I agree with you 100%. There are many things I struggle to convey these days, and sarcasm is one. My bad. But to your point that I highlighted, only in a good world with no agenda other that pure scientific inquiry. This is not a good world, and pretty much everyone has...

But they do realize medical economies like streamlined reasoning, stripped bare of some unessential, and essential, thought and effort.