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Can you explain this? It seems quite dismissive. What do you mean by perspectives, we are all focused on science here, are you implying it's OK for someone to have a non scientific opinion because, hey that's just another perspective? What concept are you referring to that you think you...

Wouldn't we all. This should be an obvious reason that exercise is futile for ME patients. If exercise made us better we would all be doing it. Unless of course we didn't want to get better. In which case, proving that exercise can make us better is pointless, our problem is we don't want to...

Article in Bloomberg on Long Covid. Nath gets a mention. Covid Long-Haulers Baffle Doctors With Symptoms Going On and On Covid Long-Haulers Baffle Doctors With Symptoms Going On and On...

Just a short anecdote - a relative of mine got Covid-19 early last year and had been feeling miserable since. They got the AZ vaccine and are now feeling much better. That's all I know. I'll try to find out more in a months time.

Sorry Grigor, normally they let you read a few articles for free every week, but this one seems to be subscriber only. Here are some excerpts :

Merged thread The Irish Times: Irish hospital doctors on long Covid: Athletic people are ‘inordinately affected’ Irish hospital doctors on long Covid: Athletic people are ‘inordinately affected’ (via @IrishTimes)...

What is "not effective enough"? How do I find post #1137? Can you link again? The question i would have is how many in the placebo group were hospitalised.

Just to say, I don't think this is the case. 70% was the average between the full dose regimen and the half initial dose. It's a made up figure with no practical use. Either someone gets the full dose and they have about a 62% chance of protection or they get the half initial dose and it's...

I am not sure but I don't think it's correct to say 53% protection. It would be a 53% chance of protection. In other words toss of a coin whether you have protection or not, if you get the Oxford vaccine. Edit: actually I think the figure is 62% Edit Edit: 62% for both full doses.

I agree with what you are saying but what about countries which won't get either the Moderna or BioNtech vaccines next year, would they be better off having a less effective AZN vaccine?

BioNtech CEO confident vaccine will work: "German pharmaceutical company BioNTech is confident that its coronavirus vaccine works against the new UK variant, but further studies are need to be completely sure, its chief executive said Tuesday. “We don’t know at the moment if our vaccine is...

Latest from BBC: The government's New and Emerging Respiratory Virus Threats Advisory Group (Nervtag) has upgraded its confidence that the new variant spreads more easily, the group's chair has said. Prof Peter Horby told a Science Media Centre briefing: "We now have high confidence that this...

BBC News - New coronavirus variant: What do we know? https://www.bbc.co.uk/news/health-55388846 In this BBC article it states "Studies by the same group suggest the deletion makes antibodies from the blood of survivors less effective at attacking the virus", with a link to paper they released...

Is there a point where a variant becomes a strain or is there a hierarchy of mutations? At what point would we be concerned that vaccines may need to be redeveloped?

Actually my issue is not concerned so much about approval, or indeed efficacy, I am just trying to figure out what they did. They don't seem to be forthcoming with information.

I can understand all that. But I don't think that was the issue here. It seems to me like it was very simple, based on the most recent BBC article : They measured the potency incorrectly. They adjusted the dose based on the incorrect potency. If that was all it was why didn't they just say...

We spend a lot of time on this forum asking questions. I think it's only fair to hold everyone to the same standard and not lower the standard just because its a covid vaccine. Sure the Oxford vaccine should bring a lot of benefit to the UK and more people around the world but that doesn't mean...

Thanks, but that implies it was just variation in the dosing. The article from BBC implies it was an intentional decision to dose at half strength based on the assumption the concentration was double what was required. It's still not clear to me.

BBC News - Oxford-AstraZeneca vaccine: Bogus reports, accidental finds - the story of the jab https://www.bbc.co.uk/news/health-55308216 More recent article about the Oxford vaccine. Interesting that they now say it was a difference in techniques in how to measure the concentration that led to...

I am not sure what more shocking - that they could make the wrong strength vaccine, that they could administer the wrong strength vaccine or that they think they can average two different groups to give a combined 70% efficacy when the original protocol specified vaccine only achieved ~60%...