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    Personal project: Sick Genes, a website for compiling significant gene findings from studies on ME/CFS and other conditions

    Great job @forestglip.:thumbup: "Keeping things as simple as possible", I second that wholeheartedly. Genetics is complicated enough even when presented as simple as possible. :hug::hug::hug: for all the spoons you've put into this.
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    Contemporary positive signs of functional limb weakness in post-acute sequelae of SARS-CoV-2: an exploratory analysis…, 2025, Osada et al.

    FND patients are educated on ingnoring symptoms, But when the patients have done the ingnoring on their own we can always blame @dave30th ? Neuro exams? no 1 stuck a needle in my upperleg and the leg was air-cycling on it's own. Normal? He could not help me. No 2 was blinded by ME/CFS in the...
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    Brain fog, cognitive dysfunction

    "struggle, unpleasant" You don't have a clue what that means in braingfog. No it ain't broken, I think. But to call it unpleasant, to me feels like you're behaving like an elephant bull in musk inside a china cupboard. I really so think you don't want to hurt anyone, but sometimes..... Brainfog...
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    Brain fog, cognitive dysfunction

    Thanks @duncan for explaining so clearly. I'm one of them too. No major intellectual impairment, maybe, but your remark hurts @Jonathan Edwards . Impaired most definitively. Feeling stupid; too often. I wasn't tested as often as you were, duncan. Only once with 2-back, 3-back over a period of...
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    Reddit - Interesting posts on Reddit, including what some doctors say about ME/CFS

    @SNT Gatchaman reported: "in the emerging value-based US healthcare system" Can someone explain this sentence to me?
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    OMF: Muscle Biopsy and Plasma Study into Post-Exertional Malaise, David Systrom, 2022

    Dr. Systrom is sending frozen biopsy samples to Amsterdam (Rob Wüst), he said in an interview. They already know about capillaries. I have diabetes and probably SFN. The neurologist I saw, left me with 3 options. Polyneuropathy or SFN or long nerve. I picked SFN. Maybe I can find a pathologist...
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    Exercise Intolerance and Response to Training in Patients With Postacute Sequelae of SARS-CoV2 Long COVID…, 2025, Cornwell et al.

    Recumbent rowing? No muscle damage as seen by Wüst and co? Picking and choosing? Cardiologists starting late in research, maybe they need some catching up first.
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    Jake Hollis - "The Fatigue Psychologist"

    As a psychiatrist you've had medical training. Jack Hollis is a PsychD, does that mean he can skip everything biomedical about ME/CFS and just promote embracing symptoms and (gradual) symptom flooding as therapy without any knowledge and accountability that goes with it?
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    The bone marrow NK-cell profile predicts MRD negativity in patients with multiple myeloma treated with daratumumab-based therapy, Korst et al. 2025

    Maybe in how many years? It would also block monoclonal antibody treatment JE wrote about. I was once offered a DNA-test because there was a suspicion of a monoclonal T-cell population, the lab did not have enough blood tot test right away. Blood draws are often problematic. I asked my GP if the...
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    The bone marrow NK-cell profile predicts MRD negativity in patients with multiple myeloma treated with daratumumab-based therapy, Korst et al. 2025

    That could mean even if there is treatment available it won't be successful in me, because of very low NK-cells:mad::cry:
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    Review What is the effect of education on fatigue in adults with neurological conditions? A systematic review and meta-analysis 2025 Simpson et al

    Why would patients need education on fatigue, they are the experts with lived experience. Pure hybris from professionals. We don't know anything, but we can educate others with ........???????? Listening to the patients would be a good place to start.
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    Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study, 2025, Friligkou et al

    What would we do without you, @forestglip?:thumbup::hug: My brain can only remember a handful. The ones with a vowel.
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    How should biological researchers present their results about ME/CFS to the media - discussion thread.

    I don't understand the anxiety gene being such a big thing. So what!! Let all the other genes do the talking. BPS is worried, why should we. I stopped taking that crowd serious anyway. The only thing they've ever done is claiming ME/CFS is psychological because the doctor's tests didn't show...
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    Genetic mechanisms, brain structures, and peripheral biomarkers mediate [...] between physical frailty and neuropsychiatric disorders, 2025, Gao et al

    Maybe a bit late for early frailty intervention after 34 years of ME/CFS. Next generations hopefully?
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    Reddit - Interesting posts on Reddit, including what some doctors say about ME/CFS

    The frustrated ones, just acting out. Probably no knowledge about ME/CFS whatsoever. Just about the patients characters, they are all the same, females. I was trained in iatrogenic damage by peads. It took 8 years to find meniscus and ligament were goners. Another 6 years to "find" a...
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    United Kingdom: ME Association news

    A mishap could happen? That's what Charles Shephard called it. Patients could die from bloodletting when they already might have a lowered blood volume.
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    Thirty Minutes to Transform Care: A Mixed-Methods Study on Brief Psychosomatic Education for Unexplained Symptoms 2025 Sioni et al

    When patients don't want CBT or GET, BPS needs to convince doctors to "find" the patients for them. A quarter of the patients "must" be MUS. (???) What to do with them, we'll find out later. (Huh)
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    Unwilling or unable? Interpreting effort task performance in myalgic encephalomyelitis/chronic fatigue syndrome, 2025, Kirvin-Quamme et al

    Nothing obnoxious about that. When it's the right answer you're allowed to quote yourself.
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    Patients with severe ME/CFS need hope and expert multidisciplinary care, 2025, Miller et al

    Is it my suspicious mind or could BPS be trying to flood the zone towards AI? Does not matter how bad the articles are as long as they are talked about?
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    Who is Simon Wessely?

    He can't spare a thought for the patients. He would be so ashamed that the only right thing to do was to return the GBE. "Sir Simon Wessely cured from his false beliefs"
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