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    USA: National Institutes of Health (NIH) intramural ME/CFS study

    Indeed! Antigens are expressed during latency for a lot of viruses, seems more common than the average GP would like to admit.
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    USA: National Institutes of Health (NIH) intramural ME/CFS study

    On second thought, with 60% not having exercise intolerance, maybe Hwang’s wasf3 findings are a bit stronger than they first came off?
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    USA: National Institutes of Health (NIH) intramural ME/CFS study

    I don’t get this. The cohort supposedly comply with 3 different sets of criteria, but then the data shows they don’t? Really strange considering multiple 2-day CPET largely confirm exercise intolerance as measurable feature.
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    News from Scandinavia

    Chief of Defence(!) to be exact, the highest ranking officer.
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    Opinion Chronic fatigue syndromes: real illnesses that people can recover from, 2023, The Oslo Chronic Fatigue Consortium

    Ironic how 'false dichotomy' has been one of the go-to talking points of a lot of these names, they clearly wouldn't recognise a dichotomy if they ever saw one the wild.
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    Opinion Chronic fatigue syndromes: real illnesses that people can recover from, 2023, The Oslo Chronic Fatigue Consortium

    Cartel would be more fitting than consortium at this point. They’re way past the threshold of vicious competition anyway. Imagine studying and researching a whole career, only to achieve a perfect display of what is so carefully described in the literature that shapes their profession as...
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    Hypothesis The viral origin of myalgic encephalomyelitis/chronic fatigue syndrome, 2023, Maureen R. Hanson

    Isn’t it wise to keep Long Covid as a variable until further though? At last there’s an opportunity to acquire large datasets with lab confirmed positive tests from within a limited timeframe. The alternative is the possibility of further muddling the same old ME/CFS pool of data. Also, the...
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    Trial Report Cardiovascular deconditioning produced by 20 hours of bedrest with head-down tilt −5° in middle-aged healthy men, 1985, Gaffney et al.

    This has been my experience too! Years of inactivity, then straight back to being in better shape than most of my friends and family who exercise regularly… I’ve abandoned exercise almost entirely due to PEM, but still preform way beyond what would be expected on the 3-4 bike rides I do in a year.
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    News from Scandinavia

    https://x.com/janetdafoe/status/1692442378466914622?s=46&t=f902mg35pswMiAw81BoXmg
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    Measuring Cognitive Exertion

    Great job, I really appreciate this initiative! I have been daydreaming along the lines of something like this as an objective endpoint for assessing PEM. I have a suggestion (which you already may have discarded in favour of computational efficiency ;)): - On the keyboard side of things...
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    Research news from Bhupesh Prusty

    I believe it was IDO metabolic trap hypothesis that got ditched. The itaconate shunt hypothesis is still on the table from my understanding, and it connects well with Prusty’s work (supposedly). Correct me if I’m wrong!
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    Lightning Process study in Norway - Given Ethics Approval February 2022

    Will anyone following this issue ever believe that Flottorp had not read the protocol? This wording to avoid liability is just so ironic when trying to meddle with the process through closed channels. Also: Befring is possibly the biggest name in health law in Norway time being. She actively...
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    WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome, 2023 Hwang et al

    The answer is usually money when it comes to this disease, but let's hope they're just incredibly confident about the effect size this time!
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    Lightning Process study in Norway - Given Ethics Approval February 2022

    Sorry, got it mixed up there, my bad. No correlation should still raise some brows, if only.. Wyllers own music therapy study did show a decrease i step count though, no?
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    Lightning Process study in Norway - Given Ethics Approval February 2022

    Especially since data from other CBT/GET trials suggest a negative correlation between subjective scoring and actual measured activity!
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    NICE and Cochrane sign collaborative agreement to deliver ‘living’ guideline recommendations

    I have a vague hope it's a reference to NICE's surfacing aspirations to school Cochrane in the basics of calculus. NICE: "So, here we have two time series from a repeated maximal grip strength test. The upper one is of patients fulfilling the Oxford criterion only, the lower one is of patients...
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    Opinion. BMJ: Long covid: research must guide future management, 2021, David

    It would sure be nice to see an honest attempt at decoupling the effects of negotiation tactics from the actual interventions in these trials. Decision-making is (arguably) one of the more robust disciples within psychology in terms of the potential of setting up actual testable hypotheses, but...
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    Chronic Fatigue Syndrome and Occupational Status: A Retrospective Longitudinal Study, 2021, Chalder et al

    Hard to decide if this is incredibly proactive, or if someone just discovered the search/replace function..
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