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Unless the CCI literature we been relying upon up until now is actually incomplete and therefore outdated, as I mentioned in my previous comments. Also, they don't base their diagnosing criteria on ME symptoms, it just happened that those symptoms are the same of ME. They've been diagnosing...

I've just replied to you about that in another thread - have these studies ever included people with both RA and ME? Because if they never included ME patients, of course these patients never presented with an ME clinical picture. I included this information because you earlier suggested that...

I did not do or say that. This is completely irrelevant to the point I was trying to make, please let's avoid confusion. What I was trying to say is: I agree that this is just an hypothesis that needs to be researched and demonstrated. However, I don't understand why in this forum the...

What if the medical literature on CCI has been wrong or simply incomplete up until now? What if there are different manifestations of CCI, depending on the personal unique physiology of each individual (maybe mechanisms as well, ex autoimmunity and bone erosion Vs genetic laxity)? Fighting in...

If RBC deformability is an issue in ME, then drugs like Pentoxifylline should improve the symptoms, shouldn't they? I'm sure they have been used in ME patients already though. https://link.springer.com/article/10.2165%2F00003495-198734010-00003 "Pentoxifylline acts primarily by increasing red...

Sorry, in that case I should have said that "they both have hemorrheologic properties" instead.

But Pentoxifylline is used to improve arterial blood flow too, and arteries seem to be big blood vessels to me. https://www.rxlist.com/consumer_pen...m#what_is_pentoxifylline_and_how_does_it_work

Ok, so you're saying that we shouldn't be believing everything that neurosurgeons and other surgeons or psychiatrists theorise and recommend as treatment within their own field of specialty, but we should take your word for it, on an online forum, without you providing any citation of evidence...

The definition of hemorrheology: hemorrheology [he″mo-re-ol´o-je] the scientific study of the deformation and flow properties of cellular and plasmatic components of blood in macroscopic, microscopic, and submicroscopic dimensions and the rheologic properties of vessel structure with which the...

We said that PTA is not effective in treating or preventing progression in Multiple Sclerosis. That was a study of the efficacy of PTA in alleviating Meniere symptoms. Are you sure that in these fifty years the understanding of pharmacodynamics of this class of drugs hasn't advanced or broadened?

It's on Wikipedia: https://en.m.wikipedia.org/wiki/Cinnarizine "Cinnarizine inhibits the flow of calcium into red blood cells, which increases the elasticity of the cell wall, thereby increasing their flexibility and making the blood less viscous.[9] This allows the blood to travel more...

My bad, I didn't see that. Well, it's not about vasodilating properties anyway. Based on what evidence are you stating this? "Someone who does not understand real physiology" how do you know? This doctor I'm referring to is a vascular surgeon whit decades of experience in his field and 10...

But how do we know that blocking these receptors is the reason why cinnarizine works in Meniere? My line of thoughts led to relating the way that Meniere was associated with CCSVI in that study, with the effects of PTA treatment and with the fact that Cinnarizine could work in Meniere in the...

The symptoms you mentioned are also classical symptoms of Meniere's disease. Stugeron is also known to be prescribed for Meniere's disease. Here's an interesting study correlating Meniere's and CCSVI: https://www.ncbi.nlm.nih.gov/m/pubmed/28034701/?i=2&from=/24594584/related "CCSVI was diagnosed...

I didn't know how to multi quote, but please see my reply to Prof. Edwards above. Again, reading lines in between paragraphs that are not there. Nobody said that Dengue is still active in this patient, like these doctors you've mentioned say. It's only been suggested Dengue as a trigger. Edit...

I think that you're still reading lines in between paragraphs that are not there. Have I ever mentioned vasodilator properties? No. I said that both stugeron and Pentoxifylline have the property of reducing blood viscosity, making the blood more "fluid". If the blood is more fluid, it will flow...

I really don't understand why you keep referring to surgical treatments here. As I explained in my previous post, Jen has never said that the patient is going to have PTA treatment or any other surgical treatment for the IJVS issue. And as I said, Zamboni admitted that PTA is not an effective...

From the article here https://onlinelibrary.wiley.com/doi/full/10.1111/cns.12859 "4 CLINICAL MANIFESTATIONS There is strong evidence showing that venous outflow abnormalities can contribute to the development of intracranial hypertension. The degree of clinical presentations of IJV outflow...

Sorry, but this seems to me to be unrelated to what is being discussed here. Nobody in these threads has never mentioned undergoing PTA treatment to cure any disease. It has been described a situation where a patient who was originally diagnosed with ME/CFS was later found to also meet the...