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Does anybody else have blue sclera? I recently noticed that the parts of my eyes that are usually white have a noticeable blue tinge to them. (I tried uploading a picture but my internet is painfully slow here, but they look like this.) I read online it could be from Ehlers danlos or...

Very interesting, thanks for chiming in. So potentially, these alert signals from peripheral tissues could be triggering hypothalamic responses, without there being any immune activation? Either way, do you think there is any chronic immune activation in ME, or more so just symptoms that...

Yes, this is what I was trying to convey, but you worded it so much better. I'm thinking similarly. The lack of elevated inflammatory cytokines and other markers of immune activation seems to point to the latter. My gut tells me that the hypothalamus is getting activated somehow, perhaps due to...

Hey all, I'm new to this board. Glad to find it. I've had ME for 11 years and have almost constant flu-like symptoms. I have a question about the immune system. So, like many, my bloodwork is normal. Normal WBC, CRP and ESR are close to zero, everything else normal. I don't believe I have any...

@Jonathan Edwards, hoping you can respond to this. Same issues as what you stated in the Goebel thread?