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  1. L

    Metabolic features and regulation of the healing cycle—A new model for chronic disease pathogenesis and treatment, Robert K Naviaux, 2018

    Depends on how damage and heal are defined. Damaged structures is not the only damage that can occur.
  2. L

    Metabolic features and regulation of the healing cycle—A new model for chronic disease pathogenesis and treatment, Robert K Naviaux, 2018

    I do not know about fibrosis but a greenisch shroud on the stool together with a dry unproductive cough in the animals were the two sighns I had to start giving them levamisole. The sooner I started the better the outcome.
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    Hyperintense sensorimotor T1 spin echo MRI is associated with brainstem abnormality in CFS, 2018, Barnden et al

    We need Michael VanElzakker
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    Hyperintense sensorimotor T1 spin echo MRI is associated with brainstem abnormality in CFS, 2018, Barnden et al

    And I think that something could come from the craninal nerves.
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    Metabolic features and regulation of the healing cycle—A new model for chronic disease pathogenesis and treatment, Robert K Naviaux, 2018

    No need to does not exclude there is.
  6. L

    Discussion - Does ME involve brain inflammation?

    I think it starts at the meninges and that changes the signaling. It is not classic inflammation.
  7. L

    Discussion - Does ME involve brain inflammation?

    When I was very severe I could go in a state I did not respond to anything. It could happen when I was sitting upright and stayed in that position. I was not the only one who had that.
  8. L

    Discussion - Does ME involve brain inflammation?

    Well when I was very severe, during flares I had something what I called a waterhead.
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    Metabolic features and regulation of the healing cycle—A new model for chronic disease pathogenesis and treatment, Robert K Naviaux, 2018

    Smart but in my case I will keep saying the causing agent is still present and can be activated by any stressor.
  10. L

    Who was it that said being in support groups leads to poor outcome?

    I second that.
  11. L

    Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns, 2018, Trivedi, Klimas et al

    Analysis of DNA methylation in promoter regions found 307 differentially methylated promoters (DMP); genes associated with DMP participate in at least 15 different pathways mostly related to cell signaling with a strong immune component.
  12. L

    Waking up in the night and hearing a brain-generated sound

    That can be very loud. If it is that I am now pretty sure that happens in the ears.
  13. L

    Psychiatry – the medical speciality that combines empathy and science

    Good question. Who knows the answer?
  14. L

    Effects of a short-term aquatic exercise intervention on symptoms and exercise capacity in individuals with CFS/ME, 2018, Broadbent et al

    I am glad my heart calmed down with improvement
  15. L

    Review: Magnesium and stress, 2018, Cuciureanu and Vink

    A human is a organism like animals and plants.
  16. L

    Ampligen for ME/CFS

    If they mean cyclic guanosine monophosphate it may help. The immune modulator levamisole I use increases cGMP.
  17. L

    Kelly McLellan seeks feedback on his draft Edinburgh ME Scale

    No. It prefends falling asleep.
  18. L

    'Shaking and trembling with ME/CFS' - Chronically Hopeful

    It was for me. It still happens during flares but it is less intense. The internal tremors have disappeared.
  19. L

    David Tuller [13/6/18]: A Curriculum for Treating CFS with CBT

    Their "treatment" is a huge stressor.
  20. L

    Question concerning XMRV

    Did he not later say there was contamination in his freezer?
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