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    3rd Annual Community Symposium on the Molecular Basis of ME/CFS at Stanford University, sponsored by OMF, 7th Sept 2019

    Of which nobody knows what influence it had.
  2. L

    Maureen Hanson talk at OMF Symposium 2019

    Yep
  3. L

    Prickling/tingling in extremities?

    Mine too
  4. L

    Prickling/tingling in extremities?

    I still get it.
  5. L

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Missailidis et al. 2019

    Good point.
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    Basic questions about metabolism

    Or a receptor disfunctious so the cells can not work properly. I think in my case the a7nAchR plays a big rule. More so since I know this receptor is on the musclulair site of the neuromusculairjunction. The immune modulator I use is a allosteric a7nAchR modulator. It reduces the pain in 10...
  7. L

    Basic questions about metabolism

    Ignore the disease process and everything will work like in healthy people.
  8. L

    Organ donation and blood donation

    Irresponsible
  9. L

    New blood test for pain

    I said my ME pain is different from injury pain.
  10. L

    Acta Neurologica Scandinavia: Inflammation and fatigue in early, untreated Parkinson's Disease - by Herlofson et al - 2019

    Cell adhesion molecules BMJ. 1999 Aug 7; 319(7206): 332–334. doi: 10.1136/bmj.319.7206.332 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1126974/
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    Scientists reverse aging process in rat brain stem cells—Nature

    I love this.
  12. L

    National Geographic: Newly discovered organ may be lurking under your skin (pain-sensing glial cells, 2019)

    Right.
  13. L

    National Geographic: Newly discovered organ may be lurking under your skin (pain-sensing glial cells, 2019)

    Depends on the definition of an organ. The skin is long accepted to be an organ. Now part of that organ is called an organ.
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    National Geographic: Newly discovered organ may be lurking under your skin (pain-sensing glial cells, 2019)

    It could be the anwser to the mystery I could not explain with what is the textbooks.
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    Machine Learning-assisted Research on ME/CFS

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162128/ Positive allosteric modulators as an approach to nicotinic acetylcholine receptor- targeted therapeutics: advantages and limitations
  16. L

    Machine Learning-assisted Research on ME/CFS

    More presice, a positive allosteric modulator. In other words , levamisole is a key for the a7nAChR backdoor.
  17. L

    Activity baseline vs activity ceiling, why concepts and language matter

    I agree.
  18. L

    Individual differences in social network size linked to nucleus accumbens and hippocampal volumes in [FND]: A pilot study, 2019, Perez et al

    Only patient-reported scales were used and social network size information was not collected for healthy subjects.
  19. L

    Machine Learning-assisted Research on ME/CFS

    The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042938/
  20. L

    Machine Learning-assisted Research on ME/CFS

    Thus, vagus nerve and cholinergic agonists inhibit systemic inflammation by activating the noradrenergic splenic nerve via the alpha7nAChR nicotinic receptors. alpha7nAChR represents a unique molecular link between the parasympathetic and sympathetic system to control inflammation. The...
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