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I think there is a potential project in getting hold of gastrointestinal biopsies (or indeed any biopsies) done on people with ME/CFS and examining them carefully for viruses and abnormalities that were either missed or reported and largely ignored. Such biopsies are typically stored for a...

Possibility of inadequate assessment From Diagnostic accuracy of computed tomography perfusion in patients with acute stroke: A meta-analysis That meta-analysis found that computed tomography to be substantially worse than MRI with DWI at detecting strokes. The pooled sensitivity of computed...

Possibility of inaccurate representation of the patient's symptoms So, bearing in mind that the authors appear to have a conflict of interest and that their paper almost certainly had to have sign off by their hospital's legal team, what evidence is there in the paper against this being a case...

I think it's worth looking at this paper for a bit, because on the face of it, FND sounds quite plausible. The case study subject reports paralysis, but tests of sensation and reflexes show that there is still nerve function, and a raised hand drop test shows that she can control the limb...

On the studies undertaken to find (latent) enteroviruses in people with ME/CFS, with a conclusion that more and better studies are needed: I think it's reasonable to hypothesise that persistent enteroviruses can cause ME/CFS, and to investigate the hypothesis. I think it's less reasonable to...

Indeed. I've had the same thoughts. I certainly hope that there is some worthwhile strategy to explain this. The Enterovirus Theory of Disease Etiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Critical Review, Hanson et al (2021) There is this 2021 review paper which...

I am (desperately) hoping that AI has taken over Maureen Hanson's identity to churn out this essay.

I'm pretty surprised by this paper, I'm really not sure what to make of it. What's with the dismissal of the idea that ME/CFS occurs after Ross River Fever and Q fever? Why the unwillingness to see people with post-Covid symptoms meeting the ME/CFS criteria as having ME/CFS? But an acceptance...