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  1. Hutan

    News from Cochrane

    There is a paywall. I'm interested to see some quotes about those points you mention.
  2. Hutan

    Cochrane Review: 'Exercise therapy for chronic fatigue syndrome', Larun et al. - New version October 2019 and new date December 2024

    This, and even then the low quality rating is only for a small number of outcomes, almost all of which are short term outcomes. The evidence for the rest of the outcomes is rated 'very low quality'. You would think that any effective treatment for chronic fatigue syndrome would have some clear...
  3. Hutan

    Patients with [long Covid] attending a multidisciplinary evaluation: Characteristics, medical conclusions, and satisfaction, Gouraud et al, 2023

    I find this a bit horrifying - here is the reality of the BPS capture of Long Covid. People with persistent symptoms, with physical incapacity, are going to this clinic for help and, according to the abstract, the response is to tell 91% to exercise. 76% appear to be diagnosed with functional...
  4. Hutan

    Petition: S4ME 2023 - Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

    A new thread has been created for the discussion of the content of Hilda Bastian's talkpage facility here: Cochrane - Exercise therapy review - Hilda Bastian's Talkpage
  5. Hutan

    Cochrane Review: 'Exercise therapy for chronic fatigue syndrome', Larun et al. - New version October 2019 and new date December 2024

    Here is the reply I posted on Hilda's talk page. A couple of my posts are not appearing on that platform, so I'm going to record them in the forum. Others might want to do the same. Hilda, You seem to be suggesting that the fact that NICE didn't rate all the evidence relating to GET as 'very...
  6. Hutan

    Cochrane Review: 'Exercise therapy for chronic fatigue syndrome', Larun et al. - New version October 2019 and new date December 2024

    From NICE https://www.nice.org.uk/guidance/ng206/evidence/g-nonpharmacological-management-of-mecfs-pdf-9265183028 page 384 This has the bit about the lack of clinically important differences for many of the outcomes. It also has the interesting news that when the NICE team had a look at the...
  7. Hutan

    Cochrane Review: 'Exercise therapy for chronic fatigue syndrome', Larun et al. - New version October 2019 and new date December 2024

    So, I make that 1. All five of the objective outcomes rated as very low quality evidence 2. Of the 20 subjective outcomes, 14 were rated as very low quality evidence. 3. Of the 25 outcomes, 19 were rated as very low quality evidence. (Possibly I didn't get them all, I didn't double check, but...
  8. Hutan

    Cochrane Review: 'Exercise therapy for chronic fatigue syndrome', Larun et al. - New version October 2019 and new date December 2024

    The NICE Guideline committee of course was labouring under the weight of a number of people who were desperate to show that BPS methods worked. And was the analysis of the trials perfect? No, it wasn't. But here are the results of the quality assessments GET versus standard care, as Hilda...
  9. Hutan

    Cochrane Review: 'Exercise therapy for chronic fatigue syndrome', Larun et al. - New version October 2019 and new date December 2024

    First, I note that NICE did not find the Larun et al 2019 review as useful: https://www.nice.org.uk/guidance/ng206/evidence/g-nonpharmacological-management-of-mecfs-pdf-9265183028 1.1.3.2 Excluded studies ... "One Cochrane review of exercise interventions (Larun 201748) pooled all exercise...
  10. Hutan

    Cochrane Review: 'Exercise therapy for chronic fatigue syndrome', Larun et al. - New version October 2019 and new date December 2024

    Below is Hilda Bastian's reply to a post by Jonathan Edwards and other posts by others that criticise the 2019 Review. This is from Hilda's talkpage, here: https://hbprojecttalk.wordpress.com/2023/11/10/welcome/comment-page-1/?unapproved=35&moderation-hash=889c3e6b14019d5b611e1b3c1401bd91 I'm...
  11. Hutan

    The effect of donepezil hydrochloride on post-COVID memory impairment: A randomized controlled trial, 2023, Pooladgar et al

    I wouldn't go so far as to say 100 participants are needed, but yes, 10 for the treatment group is just hopeless. It's worse than that, because these people had been hospitalised with Covid-19. So, there are reasons other than PCS why they might be having cognitive dysfunction. If you only...
  12. Hutan

    Persistent cognitive slowing in post-COVID patients: longitudinal study over 6 months, 2023, Martin et al

    Blue is healthy controls, pink is post-covid syndrome at baseline (an average of 13.5 months after onset) and red is post-covid syndrome 6 months later (with some attrition). Reasons for the attrition from baseline to 6 months are given as Given people who are doing an 'inpatient...
  13. Hutan

    USA: Mount Sinai PACS clinic and Dr David Putrino

    Is that irony or do you think Putrino is right not to diagnose ME/CFS if people have persisting symptoms after Covid-19 and meet ME/CFS criteria @dave30th?
  14. Hutan

    Persistent cognitive slowing in post-COVID patients: longitudinal study over 6 months, 2023, Martin et al

    Jena, Germany Clear differences in reaction time and in many tests affected by reaction time.
  15. Hutan

    USA: Mount Sinai PACS clinic and Dr David Putrino

    It's still looking like a grab bag of all sorts of things though. For a researcher trying to find a causal mechanism to talk of 'Long Covid' as it is currently defined as a useful category makes no sense to me. Maybe the loss a sense of smell and the meeting of ME/CFS diagnostic criteria and...
  16. Hutan

    USA: Mount Sinai PACS clinic and Dr David Putrino

    I'm pretty much in agreement with you SNT, but are you sure the diagnostic criteria are the same? Last time I looked, the WHO criteria for Long Covid were ridiculously non-specific. Well, maybe not ridiculously non-specific when talking about the impact of Covid-19 on health systems. But...
  17. Hutan

    USA: Mount Sinai PACS clinic and Dr David Putrino

    That makes no sense. Criteria for interventional trials can include a time and/or suspected cause of onset, along with any other criteria they want to add. So, you can have a treatment arm of 'pre-Covid-19 onset ME/CFS'. And an arm of 'ME/CFS with onset attributable to Covid-19'. Long Covid...
  18. Hutan

    Petition: S4ME 2023 - Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

    Latest update from the team running the petition: News from Cochrane, or rather from the Independent Advisory Group NOV 12, 2023 — Silence has been broken after a hiatus of more than two years in the promised monthly updates from Hilda Bastian, leader of the Independent Advisory Group (IAG)...
  19. Hutan

    ME/CFS and Long Covid charities/ organisations - International and National

    The name of the South African organisation has been updated on the basis of this as reported on the /news from South Africa thread.
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