Determining the minimum important differences for field walking tests in adults with long–term conditions: a systematic review and meta-analysis
Enya Daynes; Ruth E. Barker; Amy V. Jones; Jessica A. Walsh; Claire M. Nolan; William D-C. Man; Sally J. Singh; Neil J. Greening; Linzy...
The colloquium is underway now (Wed/Thu) and the conference on Friday. Hopefully the majority of conference talks will become available in due course. The YouTube channel is here.
Characterizing Long COVID Symptoms During Early Childhood
Rachel S. Gross and 674 others
IMPORTANCE
Recent studies have identified characteristic symptom patterns of long COVID (LC) in adults and children older than 5 years. However, LC remains poorly characterized in early childhood. This...
Actually it very much is an existent quote (on S4ME, more than once even) ;)
Onto the paper proper, and a few questions I wondered about on first read:
Given some evidence suggesting increased muscle capillary basement membrane thickening, there is a possibility that CK exiting muscle cells...
Yes I think the paper would have been easier to read if they'd written "change" instead of decrease or reduction in a number of places.
"%CO decrease >=-15%" is a bit tough to parse.
Also noting:
should read "In patients with a limited %CO reduction"
See follow-up study Postacute COVID-19 syndrome and fibromyalgia syndrome are associated with anti-satellite glial cell IgG serum autoantibodies but only fibromyalgia syndrome serum-IgG is pronociceptive (2025, PAIN)
Postacute COVID-19 syndrome and fibromyalgia syndrome are associated with anti-satellite glial cell IgG serum autoantibodies but only fibromyalgia syndrome serum-IgG is pronociceptive
Berwick, Richard J.; Sahbaie, Peyman; Kenny, Grace; Guo, Tian-Zhi; Neiland, Harvey; Andersson, David A.; Clark...
Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates
Xiao Yan; David Kuster; Priyesh Mohanty; Jik Nijssen; Karina Pombo-García; Jorge Garcia Morato; Azamat Rizuan; Titus M. Franzmann; Aleksandra Sergeeva; Anh M. Ly; Feilin Liu; Patricia M. Passos; Leah...
"In part, due to concerns about […] stigmatization (with CBT)."
What on earth are they talking about?
(Also, they've clearly spent so much time on Twitter that they've lost the ability to write in full sentences.)
Study of a monoclonal antibody to ancestral and early variant SARS-CoV-2, with inclusion criteria being LC 2 years out from Covid contracted prior to Aug 2022. 24 patients got AER002 and 12 patients got placebo.
No significant difference in primary endpoint (PROMIS-29) and all secondary...
I don't think it would be particularly helpful for general availability here. The details are directed to lab researchers. Having the abstracts and knowing the book is available is probably all that's needed.
Sympathetic Neural Overdrive, Vascular Dysfunction and Diminished Exercise Capacity in Long COVID-19 Patients: A Long-Term Study of Cardiovascular Sequelae (2025, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology) —
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