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  1. SNT Gatchaman

    News from Aotearoa/New Zealand and the Pacific Islands

    More unhelpful LP promoting BS. Doesn't mention LP, instead referring to "the neuro-linguistics course". Does refer to Modern Neuroscience™. https://thespinoff.co.nz/society/18-06-2025/chronic-fatigue-and-me-the-reality-of-a-torrid-illness-and-light-at-the-end-of-the-tunnel
  2. SNT Gatchaman

    Who is Simon Wessely?

    "But the most important thing of all has been the privilege to work with such generous, talented and extraordinary colleagues over all these years. My thanks to each and every one of you." Spare a thought for the patients guv?
  3. SNT Gatchaman

    Butyrate enhances CD56 NK cell-driven killing of activated T cells and modulates NK cell chromatin accessibility, 2025, Federico Carlini et al

    See also Butyrate Selectively Targets Super-Enhancers and Transcriptional Networks Associated with Human Mast Cell Function (2025, European Journal of Immunology)
  4. SNT Gatchaman

    Butyrate Selectively Targets Super-Enhancers and Transcriptional Networks Associated with Human Mast Cell Function, 2025, Folkerts et al.

    Butyrate Selectively Targets Super-Enhancers and Transcriptional Networks Associated with Human Mast Cell Function Jelle Folkerts; Marjolein J. W. de Bruijn; Wilfred F. J. van IJcken; Rudi W. Hendriks; Ralph Stadhouders Mast cells are key drivers of allergic inflammation. We have previously...
  5. SNT Gatchaman

    Webinar: Understanding ME: Investigating cellular and body-wide features of ME, Dr Daniel Missailidis, PhD

    Shower thoughts == best thoughts. Maybe something about water running on your scalp and nothing to do but stand/gently sway. I'm glad I can stand in the shower longer these days: being tragically curled up in the shower tray for a couple of minutes and crawling out does not lead to the same...
  6. SNT Gatchaman

    Review Mitochondrial innate immune signaling in skeletal muscle adaptation to exercise, 2025, Ma, Hwang et al.

    I excluded the reference numbers in the quote, but it's "With this insight, a drug with STING antagonist properties could be considered as part of the treatment strategy [85]" [85] STING Agonists/Antagonists: Their Potential as Therapeutics and Future Developments (2022, Cells) [Open Access]
  7. SNT Gatchaman

    Review Mitochondrial innate immune signaling in skeletal muscle adaptation to exercise, 2025, Ma, Hwang et al.

    See — CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise (2023) Jin Ma; Ping-yuan Wang; Jie Zhuang; Annie Y. Son; Alexander K. Karius; Abu Mohammad Syed; Masahiro Nishi; Zhichao Wu; Mateus P. Mori; Young-Chae Kim; Paul M. Hwang Link | PDF...
  8. SNT Gatchaman

    Review Mitochondrial innate immune signaling in skeletal muscle adaptation to exercise, 2025, Ma, Hwang et al.

    Mitochondrial innate immune signaling in skeletal muscle adaptation to exercise Jin Ma; Annie Yujin Son; Youlim Son; Ping-yuan Wang; Paul M. Hwang Exercise-induced inflammation is regarded as a response to muscle damage from mechanical stress, but controlled immune signaling can be beneficial...
  9. SNT Gatchaman

    Preprint Dissecting the genetic complexity of myalgic encephalomyelitis/chronic fatigue syndrome via deep learning-powered genome analysis, 2025, Zhang+

    We should keep a wide purview. While many of these genes are flagged as neural and relating to synaptic function, they can have important non-canonical roles. The potential link with autism development is fascinating but autism spectrum disorder has other features beyond the neurodevelopmental...
  10. SNT Gatchaman

    COVID-19 induces persistent transcriptional changes in adipose tissue that are not associated with Long COVID, 2025, DeLine-Caballero, Rosen, Blish+

    COVID-19 induces persistent transcriptional changes in adipose tissue that are not associated with Long COVID Soneida DeLine-Caballero; Kalani Ratnasiri; Heping Chen; Seynt Jiro Sahagun; Uma M. Mangalanathan; Trisha R. Barnard; Nicole Turk; Jasmine Yang; Natesh Saini; Ekrem M. Ayhan; Hasiyet...
  11. SNT Gatchaman

    Preprint SARS-CoV-2-induced dysregulation in ADAR editing patterns persists post viral clearance in individuals with mild COVID-19, 2025, Nair & Piontkivska

    SARS-CoV-2-induced dysregulation in ADAR editing patterns persists post viral clearance in individuals with mild COVID-19 Aiswarya Mukundan Nair; Helen Piontkivska Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections remain a public health concern worldwide. Viral antigen...
  12. SNT Gatchaman

    Psychology Today: In Search of a Coherent Understanding of ME/CFS and Long Covid, Jake Hollis

    (Can the new forum software give us a vomit emoji button in addition to the like button?) And everyone else's.
  13. SNT Gatchaman

    Patients with severe ME/CFS need hope and expert multidisciplinary care, 2025, Miller et al

    That's not the claim. i.e. "And if [changing their mindset does lead to recovery], then the diagnosis of ME/CFS was simply wrong."
  14. SNT Gatchaman

    SARS-Cov-2 Replication in a [Blood–Brain Barrier Model] Induces Permeability & Disables [ACE2] Regulation of Bradykinin B1 Receptor, 2025, Coelho+

    SARS-Cov-2 Replication in a Blood–Brain Barrier Model Established with Human Brain Microvascular Endothelial Cells Induces Permeability and Disables ACE2-Dependent Regulation of Bradykinin B1 Receptor Coelho, Sharton Vinicius Antunes; Souza, Gabriela Lisboa e; Bezerra, Bruno Braz; Lima, Luan...
  15. SNT Gatchaman

    Children with Post COVID-19 Multisystem Inflammatory Syndrome Display Unique Pathophysiological Metabolic Phenotypes, 2025, Lawler, Yonker, Nicholson+

    Children with Post COVID-19 Multisystem Inflammatory Syndrome Display Unique Pathophysiological Metabolic Phenotypes Nathan G. Lawler; Lael M. Yonker; Samantha Lodge; Philipp Nitschke; Maureen M. Leonard; Nicola Gray; Luke Whiley; Reika Masuda; Elaine Holmes; Julien Wist; Alessio Fasano; Jeremy...
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