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Doherty Institute: Real-time study to reveal crucial facts about persistent illnesses post-COVID Link to The OUTPOST Study.

Multidimensional Characterization of Long COVID Fatigue Matthew B. Maas; Kathryn J Reid; Millenia Jimenez; Melissa Lopez; Janet Miller; Mercedes R Carnethon; Phyllis C Zee; Kristen L Knutson; Igor J Koralnik OBJECTIVES We performed a multidimensional analysis of mood, cognition, sleep and...

ETS1 also came up in Genetic risk factors for severe and fatigue dominant long COVID and commonalities with ME/CFS identified by combinatorial analysis (2023, Journal of Translational Medicine) which used the PrecisionLife combinatorial analysis platform. 30.5% of their severe LC cohort showed...

Imagine sending children with tetralogy of Fallot, who quite distinctively learn to squat as a compensation, off to psychobehavioural re-education. First observed by Helen Taussig. From Medscape —

She very much is. But often paper sections are divided up and one person's section and thinking can end up being in contention with others. Sometimes paper writing groups form up with subsequent dropouts and later additions to the group, or the lead author wants a particular spin. I was...

Tags: cell-free dna (and neutrophil extracellular traps)

Bedeutung von „avoidance“ und „endurance“ beim Post-COVID-Syndrom Kupferschmitt, Alexa; Herrmann, Christoph; Jöbges, Michael; Kelm, Stefan; Sütfels, Gerhard; Loew, Thomas H.; Hasenbring, Monika; Köllner, Volker BACKGROUND The importance of dysfunctional coping strategies in the chronification...

The Times: ‘RFK Jr is a disaster’: Staff describe chaos in ‘anti-science’ regime (archive)

Sleep need–dependent plasticity of a thalamic circuit promotes homeostatic recovery sleep Sang Soo Lee; Qiang Liu; Alexandra H. R. Cheng; Dong Won Kim; Daphne M. Boudreau; Anuradha Mehta; Mehmet F. Keles; Rafal Fejfer; Isabelle Palmer; Kristen H. Park; Heike Münzberg; Timothy D. Harris; Austin...

Doubt the same will be able to be said of Alan Carson's upcoming comment.

Came across this series from a month back from an NHS orthopaedic surgeon and departmental clinical director. I won't put the quotes behind a spoiler as I think people are familiar with this thread and what we're up against, but worth recording. Caution: ahead there be dragons Link |...

Thank you for emphasising this point @Janna Moen PhD

Neuroimmune pathophysiology of long COVID Janna K. Moen; Christopher A. Baker; Akiko Iwasaki Although COVID-19 was originally considered a respiratory illness, it is now well established that SARS-CoV-2 infection can have far-reaching impacts on the nervous system. Neurological symptoms such as...

Direct links — Link | PDF (British Columbia Medical Journal) [Open Access]

(In mice)

Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation White, Zachary; Cabrera, Ivan; Mei, Linghan; Clevenger, Margarette; Ochoa-Raya, Andrea; Kapustka, Isabel; Dominguez, Joseph R.; Zhou, Jinyan; Koster, Kevin P.; Anwar, Shehata; Wang, Qianxun; Ng, Charles; Sagoshi...

Just looking at the first one, NBPF1 also has high expression outside the nervous system, including in bone marrow, lymph nodes and skeletal muscle. https://www.genecards.org/cgi-bin/carddisp.pl?gene=NBPF1#expression

Long term effect of COVID-19 on brain metabolism and connectivity Beatrice Bravi; Marco Paolini; Federica Colombo; Mariagrazia Palladini; Valentina Bettonagli; Mario Gennaro Mazza; Rebecca De Lorenzo; Patrizia Rovere-Querini; Francesco Benedetti; Sara Poletti AIMS After 3 years from the...