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Adenomyosis (and endometriosis) are common. Figure from the 2022 consensus guidelines for typical ultrasonographic appearance — Consensus on revised definitions of Morphological Uterus Sonographic Assessment MUSA features of adenomyosis: results of modified Delphi procedure M. J. Harmsen; T...

Modulating the PI3K Signalling Pathway in Activated PI3K Delta Syndrome: a Clinical Perspective (2023) Berglund, Lucinda J. Activated phosphoinositide-3-kinase (PI3K) δ syndrome (APDS) is an inborn error of immunity characterised by immune dysregulation. Since the discovery of genetic mutations...

It's hard to imagine there's some static threshold. I can experience light hypersensitivity some days in the later evening and I have the lights down very low and my wife has to read her iPad in dark mode/dim when next to me. At other times this symptom is not present. So it's variable across...

Peripheral leptin receptor gene network modulates the impact of childhood adversity on mental health disorders Sobreira de Lima; Barth; Arcego; de Mendonça Filho; Patel; Wang; Elgbeili; Pokhvisneva; Parent; Levitan; Kobor; Dalmaz; Silveira Psychiatric disorders are highly prevalent and often...

SARS-CoV-2 MA10 Infection Aggravates Cerebrovascular Pathology in Endothelial Nitric Oxide Synthase-Deficient Mice Ismael, Saifudeen; Umar, Meenakshi; Ouvrier, Blake; Hall, Gregory; Cummins, McKenzie; Sapkota, Arjun; Talkington, Grant; White, Amanda Louise; Milner, Richard; Khismatullin, Damir...

Quantifying all-cause healthcare resource utilization and costs of children with mild-to-moderate long COVID in France Jingyan Yang; Cheikh Tamberou; Elise Arnee; Pierre-Alexandre Squara; Ayoub Boukhlal; Jennifer L. Nguyen; Hannah R. Volkman; Stephane Fievez; Marina Lepoutre-Bourguet; Haifa Ben...

That would be the jade egg (maybe also the infamous candle).

Beyond mood screening: a pilot study of emotional, cognitive, and somatic concerns in patients with Long COVID Sorets, Tali R. ; Finley, John-Christopher A. ; LaFrance, W. Curt ; Patten, Ryan Van ; Mordecai, Kristen ; Jimenez, Millenia ; Suchy, Stephen ; Cahan, Joshua ; Koralnik, Igor J. ...

Somewhat repeating points in the abstract, but this is from the body text —

Fortunately somewhat balanced by Myalgic Encephalomyelitis/Chronic Fatigue Syndrome is common in post-acute sequelae of SARS-CoV-2 infection PASC: Results from a post-COVID-19 multidisciplinary clinic (2023) Incidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the...

As above they've completely misunderstood PEM. What's wrong with defining tiredness as simply "wanting to sleep"?

Improvement of Fatigue and Body Composition in Women with Long COVID After Non-Aerobic Therapeutic Exercise Program Miana, María; Moreta-Fuentes, Ricardo; Jiménez-Antona, Carmen; Moreta-Fuentes, César; Laguarta-Val, Sofía BACKGROUND/OBJECTIVE Fatigue is one of the most recurrent and most...

So, while aiming to evaluate activated fibroblasts in lung, they noted uptake in the paravertebral muscles that happened to be in the imaging range. This is something Rob Wüst and Anouk Slaghekke will be interested in given their poster presentation on collagen IV deposition in muscle...

[18] is Muscle abnormalities worsen after post-exertional malaise in long COVID (2024)

Indeed. Hence "education".

"Notably, our study did not uncover any differentially expressed IFN genes"

In the thread Replicated blood-based biomarkers for myalgic encephalomyelitis not explicable by inactivity (2025) — I haven't watched yet but I think the video is available on YouTube at —

If I've read correctly there seem to be some opposite findings to those in ME/CFS, eg In vitro B cell experiments explore the role of CD24, CD38, and energy metabolism in ME/CFS (2024) There are both similarities and differences in this FM paper wrt naive B-cell proportions (increased in...