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Section 5 of the Prevention of Future Deaths Report (my bolding) — CORONER’S CONCERNS During the course of the inquest the evidence revealed matters giving rise to concern. In my opinion there is a risk that future deaths will occur unless action is taken. In the circumstances it is my...

Molecular Insights into Long COVID: Plasma Proteomics Reveals Oxidative Stress, Coagulation Cascade Activation, and Glycolytic Imbalance Sheela Ramanathan; Mohammad Mobarak Hussain Chowdhury; Akouavi Julite Irmin Quenum; Christine Rioux-Perreault; Jean-Francois Lucier; Subburaj Ilangumaran...

I'd definitely include that study. It's clear she has ME/CFS. The authors seem to be arguing that ME/CFS requires no alternative cause to explain symptoms and they found the cause in this specific patient. There's a hint that they think ME/CFS is psychobehavioural, so that finding a biological...

That looks fantastic @forestglip :thumbsup::thumbsup: A lot of work, but I'm going to be referring back to this quite I think. Great having the link to the S4ME thread too. You might like to strip the last eg "/page-2" (when sometimes present) in the URL, to link to the start of each thread...

Brain endothelial gap junction coupling enables rapid vasodilation propagation during neurovascular coupling Trevor Krolak; Luke Kaplan; Kathleen Navas; Lujing Chen; Austin Birmingham; Daniel Ryvkin; Victoria Izsa; Megan Powell; Zhuhao Wu; Benjamin E. Deverman; Chenghua Gu To meet the brain's...

A data-mining analysis of host solute carrier family proteins in SARS-CoV-2 infection with reference to brain endothelial cells and the blood-brain barrier in COVID-19 Fradkin, Talia ; Schmidt-Kastner, Rainald BACKGROUND The brain vasculature is a key player in neurological manifestations of...

Phenotypic characteristics of peripheral immune cells of Myalgic encephalomyelitis/chronic fatigue syndrome via transmission electron microscopy: A pilot study (2022)

Probably some useful data, but the usual poor attention to detail and logic in the write up. That abstract could have benefited from even a single read through. But apart from the grammar, how does the conclusion in the paper — which follows this discussion — lead to this conclusion in...

Single-cell RNA-sequencing highlights a curtailed NK cell function in convalescent COVID-19 pregnant women Salker, Madhuri S. ; Abd Aziz, Nor Haslinda ; Prodan, Natalia Carman ; Yang, Zhiqi ; Lankapalli, Aditya Kumar ; Lazar, Katrin ; Shafiee, Mohamad Nasir ; Kocak, Ersoy ; Ganesan, Harivignesh...

SciHub

I haven't read this paper yet, but yes I question some of the presumed non-infectious triggers which might have been acutely asymptomatic infections, but then retrospectively attributed to things like a period of increased work or family stress. But I would certainly leave open the possibility...

Association between Adverse Childhood Events ACEs and long-term COVID-19 symptoms: evidence from the 2022 behavioral risk factor surveillance system Elkefi, Safa; Steffen, Alana; Matthews, Alicia K. OBJECTIVE This study investigated the association between Adverse Childhood Events (ACEs) and...

Previous papers under the dti-alps tag. And a previous list of papers here. I nearly did an automagical acronym post for this one too @Hutan — ALPS Along the perivascular space (MRI Diffusion technique: glymphatics) BPI Brief pain inventory CMI Chronic multisystem illness (cf Gulf war illness)...

DTI-Derived Evaluation of Glymphatic System Function in Veterans with Chronic Multisymptom Illness Yu Zhang; Matthew S. Moore; Yashar Rahimpour; J. David Clark; Peter J. Bayley; J. Wesson Ashford; Ansgar J. Furst BACKGROUND AND PURPOSE Chronic Multisymptom Illness includes symptoms of fatigue...

Hi @nataliezzz and welcome. One thing that has become very clear with the SARS2 pandemic is the large (~40%) number of acutely asymptomatic infections. A proportion of these patients have gone on to ME/CFS. Without looking in depth at someone's viral history, eg via T cell immune profiling...

Reddit thread from a pwVSME in Spain: I'm losing weight at light speed and I'm desperate - Quick update about Alicia

From Wikipedia — Recent review — YKL-40 as a biomarker in various inflammatory diseases: A review (2024, Biochemia Medica)

Not in New Zealand. Vaccine-induced ME/CFS occurred before there was community transmission of SARS-CoV-2 (beyond some isolated and controlled outbreaks). We should have been studying our population to understand the immune response once Omicron was "let rip" into a well vaccinated but...

So what is PG's view on multiple sclerosis? Are MS patient charities promoting permanence and dismissal of mind-body approaches and do they also risk exploiting vulnerable people while they dismiss recovery and promote a wait-for-a-drug narrative? After all we have similarly well-evidenced...

You can. I haven't done many but had no complications. My experience was with HIV+ and oncology patients.