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Which is not to say there hasn't been a surge in disability - just that the majority weren't insured. Eg younger adults at the start of employment, perhaps trying to pay off student loans or save for a house. Other socio-economic factors I can imagine at play would be a married couple that has...

On Bluesky Dr Janet Scott posts —

Link minus the Facebook tracking – https://www.health.govt.nz/system/files/2025-05/models-care-people-living-with-long-covid.pdf Thanks @Deanne NZ I wonder if we should start a new thread. It has the usual mix of good and bad points on initial skim. One good being listing the potential...

Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 PASC in nonhuman primates Long-term adverse consequences of SARS-CoV-2 infection, termed “long COVID” or post-acute sequelae of COVID (PASC), are a major component of overall...

It should be noted that this has been published in Nature Medicine, which might help get the biomedical context of ME/CFS under the noses of physicians. FWIW Nature Medicine has a higher impact factor than Nature itself (58.7 vs 50.5 for 2023). By comparison Deep phenotyping of post-infectious...

https://www.change.org/p/the-nhs-must-take-measures-to-stop-dill-deteriorating

Also via her BlueSky account.

Immune-Metabolic Programs Drive Disease Trajectories in Paediatric Long COVID While most children and adolescents recover uneventfully from SARS-CoV-2 infection, some develop persistent symptoms known as paediatric long COVID (LC). Paediatric LC presents with substantial, multisystem health...

Link to published paper here Preprint: Heightened innate immunity may trigger chronic inflammation, fatigue and post-exertional malaise in ME/CFS Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by unexplained fatigue, post-exertional malaise (PEM), and cognitive...

Long COVID and its associations with burnout, anxiety, and depression among U. S. healthcare workers in the United States BACKGROUND Data on Long COVID and its associations with burnout, anxiety and depression among healthcare workers (HCW) in the United States (U. S.) is limited. METHODS...

The cognitive training is referenced as Adaptive vs. non-adaptive cognitive training by means of a personalized App: a randomized trial in people with multiple sclerosis (2016, Journal of NeuroEngineering and Rehabilitation)

A randomized comparative feasibility study of neuromodulation and cognitive training for post-COVID fatigue Fatigue and cognitive deficits are common and disabling symptoms in patients experiencing post-COVID condition. This randomized parallel study aimed to evaluate the effects of...

Mast cells regulate the brain-dura interface and CSF dynamics Cerebrospinal fluid (CSF) flow is essential for brain homeostasis, and its disruption is implicated in neurodegenerative and neuroinflammatory diseases. Arachnoid cuff exit (ACE) points, anatomical discontinuities in the arachnoid...

A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis The immune environment surrounding the brain plays a fundamental role in monitoring signs of injury. Insults, including ischemic stroke, can disrupt this balance and incite an exaggerated inflammatory response...

Reminder that PubMed will be undergoing maintenance and offline for 24 hrs+ from 9pm EDT 25/7/25 (0100 UTC).

Not clicking that link ! Primary Link | Archive

Imma stop you there.

The Effects of a Mindfulness-Based Intervention on Depression and Anxiety in the Long-COVID Population Long-COVID is a complicated, post-viral syndrome involving multiple body systems and can present with neuropsychiatric symptoms. Little has been reported about the neuropsychiatric symptoms...

Systrom — Mitochondrial biomass is down in all. (This is opposite to genetic primary mitochondrial myopathies where biomass increases to compensate.) Then you have two subsets: high systemic O2 extractors and low systemic O2 extractors (at peak exercise). Predicated on unimpaired or impaired...