Except it may not be damage. (In the same way T cell subset exhaustion markers do not mean globally tired T-cells.)
The changes in diffusivity might not indicate neuroinflammation or cell damage. It could relate to myelin maintenance and even be compensatory, ie increased or decreased to...
Published in July —
Distinct white matter alteration patterns in post-infectious and gradual onset chronic fatigue syndrome revealed by diffusion MRI
While post-infectious (PI-ME/CFS) and gradual onset (GO-ME/CFS) myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) manifest similar...
Missed this one at the beginning of last year, but it was referenced in Interrogating pulmonary diffusing capacity in long COVID: insights from DLCO and DLNO testing (2025)
Symptomatic post COVID patients have impaired alveolar capillary membrane function and high VE/VCO2
BACKGROUND
Post COVID-19 syndrome is characterized by several cardiorespiratory symptoms but the origin of patients reported symptomatology is still unclear.
METHODS
Consecutive post COVID-19...
Safety and Effectiveness of an Exercise-Based Telerehabilitation Program in Myalgic Encephalomyelitis and Post COVID Syndrome: Protocol for a Randomized Controlled Clinical Trial
BACKGROUND/OBJECTIVES
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Post-COVID Syndrome (PCS) are...
It's CSF flow during the cardiac cycle through the cerebral aqueduct (between third and fourth ventricles). It goes 3 → 4 in systole with a bit of regurgitant/retrograde flow 4 → 3 in diastole.
I've annotated a screengrab from
Green marks the aqueduct. Red arrow shows direction of the larger...
Inflammation from mild COVID-19 results in persistent neurological and behavioral changes in rhesus macaques
Although most SARS-CoV-2 infections result in mild or moderate symptoms not requiring hospitalization, many patients experience persistent symptoms after their initial recovery, a...
Blood pro-thrombotic analytes and platelet activation are associated with post-acute sequelae of COVID-19
Post-Acute Sequelae of COVID-19 (PASC), or “long COVID,” describes persistent symptoms following recovery from SARS-CoV-2 infection. Early identification of circulating biomarkers...
Association of Autonomic Dysfunction With Long COVID: Evaluation Using Quantitative Autonomic Testing
BACKGROUND
Persistent symptoms (eg, heart palpitations, lightheadedness, fatigue) despite resolution of acute COVID-19 infection is termed “long COVID syndrome” or simply “long COVID.” Long...
Omics-based computational approaches for biomarker identification, prediction, and treatment of Long COVID
Long COVID, or post-acute sequelae of COVID-19 (PASC), is a major global health problem, with cumulative estimates suggesting that around 400 million people worldwide have been affected...
Interrogating pulmonary diffusing capacity in long COVID: insights from DLCO and DLNO testing
INTRODUCTION
The lingering respiratory effects of COVID-19, particularly in patients with Long COVID, remain poorly understood, prompting a comprehensive evaluation of lung function in this...
Neurofluid circulation changes during a focused attention style of mindfulness meditation
Neurofluids, including cerebrospinal fluid (CSF) and interstitial fluid, circulate through regulated central nervous system pathways to clear cerebral waste and support brain health, with elevated CSF...
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