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The potential bidirectional relationship between long COVID and menstruation Women have reported menstrual changes following SARS-CoV-2 infection and variation in long COVID symptoms across the menstrual cycle. We examined (i) whether COVID is linked to abnormal uterine bleeding (AUB), (ii) if...

Dysregulated oxidative stress and lactate levels in treatment-resistant schizophrenia Fang; Zhang; Xu; Wang; He; Liao; Yuan; Tang Schizophrenia is a severe and clinically heterogeneous mental disorder, with approximately 30 % of patients developing treatment resistance to standard...

Choroid plexus alterations in autism spectrum disorder: A PET-MRI study The choroid plexus (CP), primarily known as the production site of cerebrospinal fluid (CSF), constitutes one of the sites of the blood-CSF barrier and plays a unique role in inflammation propagation, serving as a key...

Except don't forget CSF is a lot closer to CNS tissue than blood. Apart from the blood-brain barrier, there's also proximity and dilution. So we might currently only be able to evaluate this compartment [edit: ie liquid biopsy in comparison to blood]. It's possible we might see similarly...

RACK1 UBC PPIA LAPTM5 FBXO2 CRYM Many familiar faces in terms of pathways: ubiquitin, lysosomes, haem, amino acid and lipid metabolism. Note the over log2 20 fold-change up-regulation of BTN2A3P in CSF. BTN2A2 and BTN2A3 were tier 1 hits with DecodeME.

Identification of ultra-rare genetic variants in pediatric acute onset neuropsychiatric syndrome PANS by exome and whole genome sequencing Abrupt onset of severe neuropsychiatric symptoms including obsessive–compulsive disorder, tics, anxiety, mood swings, irritability, and restricted eating...

Varying Levels of Inflammatory Activity in Brain and Body of Patients with Persistent Fatigue and Difficulty Concentrating After COVID-19: A TSPO PET Study A significant number of patients report persistent fatigue and difficulty concentrating after infection with severe acute respiratory...

HLA-B*15:01-positive severe COVID-19 patients lack CD8+ T cell pools with highly expanded public clonotypes Understanding host factors driving asymptomatic versus severe disease outcomes is of key importance if we are to control emerging and re-emerging viral infections. HLA-B*15:01 has been...

See also Dysregulation of innate immunity and cellular metabolism through virus-induced deISGylation (2025)

See also A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID (2025)

Dysregulation of innate immunity and cellular metabolism through virus-induced deISGylation Interferon-stimulated gene 15 (ISG15) regulates diverse cellular responses including antiviral immunity through its conjugation to proteins, a process known as ISGylation. Several pathogens, including...

Now published — Web | PDF | Frontiers in Physiology | Open Access

Previous mentions of Bartholomew on S4ME here and here.

An article was even published in The Conversation: Mass hysteria at Heathrow airport – how social contagion works Somewhat ironically this was written by a member of IndieSAGE, and included this passage on misinformation —

Guardian (8/9/25) Mass psychogenic illness’ plausible cause of toxic substance alert at Heathrow, says scientist Guardian (9/9/25) Man arrested on suspicion of bringing teargas to Heathrow airport --- "One Day Later"