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  1. SNT Gatchaman

    Scientists just found cancer cells’ hidden power source

    Mitochondria-derived nuclear ATP surge protects against confinement-induced proliferation defects The physical tissue microenvironment regulates cell state and behaviour. How mechanical confinement rewires the subcellular localisation of organelles and affects cellular metabolism is largely...
  2. SNT Gatchaman

    Preprint Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome, 2025, DecodeMe Collaboration

    That's a really useful article @ME/CFS Science Blog - thank you. Looking forward to the next in the series. I'll try and find some articles that tie identified genes to the new post-synaptic AMPA receptor findings (X looks like it marks the spot quite nicely). I spotted one instance of...
  3. SNT Gatchaman

    Prevalence and Clinical Impact of Postural Orthostatic Tachycardia Syndrome in Highly Symptomatic Long COVID, 2025, Björnson et al.

    Prevalence and Clinical Impact of Postural Orthostatic Tachycardia Syndrome in Highly Symptomatic Long COVID BACKGROUND The incidence of postural orthostatic tachycardia syndrome (POTS) in long COVID has been a growing concern since the first cases were reported in 2021. The aim of this study...
  4. SNT Gatchaman

    Review Erythrocytes as a Source of Exerkines, 2025, Misiti et al.

    Erythrocytes as a Source of Exerkines Exercise activates many metabolic and signaling pathways in skeletal muscle and other tissues and cells, causing numerous systemic beneficial metabolic effects. Traditionally recognized for their principal role in oxygen (O2) transport, erythrocytes have...
  5. SNT Gatchaman

    Preprint Immunological and non-immunological features specific to Long-COVID: multiple overlapping aetiologies and potential biomarkers, 2025, Ponchel

    That's the corresponding author. It's a consortium involving researchers in UK, Ireland, The Netherlands, France and US. Patient numbers were relatively small though.
  6. SNT Gatchaman

    News from Scotland

  7. SNT Gatchaman

    Exploring Alice in Wonderland syndrome in adults with persistent headache after COVID-19: a cross-sectional study in Latin America, 2025, Carrión-Ness

    Exploring Alice in Wonderland syndrome in adults with persistent headache after COVID-19: a cross-sectional study in Latin America BACKGROUND Alice in Wonderland syndrome (AIWS) is a neuropsychiatric disorder characterized by sensory perception distortions, including altered body image...
  8. SNT Gatchaman

    Long COVID After Acquisition of the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 SARS-CoV-2 During Pregnancy Compared With Outsi

    Long COVID After Acquisition of the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 SARS-CoV-2 During Pregnancy Compared With Outside of Pregnancy OBJECTIVE To evaluate whether the risk of long COVID among individuals infected with severe acute respiratory syndrome...
  9. SNT Gatchaman

    Systemic increase of AMPA receptors associated with cognitive impairment of long COVID, 2025, Fujimoto et al.

    Coincidentally announced today is FDA approval for a phase 2 study on AMPAR modulation from a Welsh biotech. Note that this is upregulating AMPAR function, impaired in depression. See https://en.wikipedia.org/wiki/AMPA_receptor_positive_allosteric_modulator
  10. SNT Gatchaman

    Circulating Microclots Are Structurally Associated With Neutrophil Extracellular Traps and Their Amounts Are Elevated in [LC] Patients, 2025, Thierry+

    Now published as — Circulating Microclots Are Structurally Associated With Neutrophil Extracellular Traps and Their Amounts Are Elevated in Long COVID Patients The persistence of vasculo-thrombotic complications has been put forward as a possible contributing factor in the Long COVID (LC)...
  11. SNT Gatchaman

    Polygenic and developmental profiles of autism differ by age at diagnosis, 2025, Zhang et al.

    Polygenic and developmental profiles of autism differ by age at diagnosis Although autism has historically been conceptualized as a condition that emerges in early childhood1,2, many autistic people are diagnosed later in life3,4,5. It is unknown whether earlier-and later-diagnosed autism have...
  12. SNT Gatchaman

    Effect of 8-week exercise-based rehabilitation on immune cell counts in Post-COVID syndrome following hospitalisation: a RCT, 2025, Bishop

    No they do not, they're more worried about those tired T cells. And in severe acutely hospitalised patients.
  13. SNT Gatchaman

    Effect of 8-week exercise-based rehabilitation on immune cell counts in Post-COVID syndrome following hospitalisation: a RCT, 2025, Bishop

    Lead author (along with Chalder and 40 others) of Post-Hospitalisation COVID-19 Rehabilitation PHOSP-R: A randomised controlled trial of exercise-based rehabilitation (2025)
  14. SNT Gatchaman

    Systemic increase of AMPA receptors associated with cognitive impairment of long COVID, 2025, Fujimoto et al.

    This paper looks to be of importance, particularly given DecodeME’s identification of synapse-related genes. Before delving into findings some framing through the paper is notable.
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