Edit: I haven't been able to read all the discussion. The PACE trial used the Oxford criteria for CFS, which only requires chronic disabling...
But it doesn't @Medfeb. If an anti-inflammatory analgesic is studied in large trials of joint pain do we then say that it should not be...
Notable that since this follows, this has been Garner's most recent promotional tour. Out of some trial on LC that doesn't actually say that, but...
...of the individual that put them in a subset - like PEM. But the PACE trial selection criteria are justified on the basis that if it gave a...
...in a clinic, diagnosed under the 2007 NICE guideline and PACE trial results in 2011. My form filling was worse on fatigue but I felt better on...
Can you offer a guest editorial? I honestly can't understand how this situation prevails. It's frankly weird how doctors are expected to be...
But when is this taught? I've taken methodology classes with medical students, and I've only ever really heard about this problem in the ME...
...reminding people that when I presented my thoughts about the PACE trial to the University College London Division of Medicine (cardiologists,...
It goes back much further than PACE. BPS supporters have been in key positions at Cochrane from the start, as I understand it. And they determined...
...review left to the BPS lobby in the first place? Surely the PACE trial displayed a need to control the narrative around how data is being...
PACE had an objective measure of physical fitness (which involved patients doing a step-test while having their oxygen measured, IIRC) and there...
Week beginning 30th December 2024 Science for ME petition Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review Update: On...
...Monaghan SNP read out in the Westminster Hall debate in 2018, an extract of a letter she received from someone who participated in the PACE trial.
It's really impressive how this is 100% textbook pseudoscience, you could teach an entire philosophy program dedicated to misinformation,...
And yet, they have caused harm. Not least by diverting funds and effort away from collecting useful information. But also in diminishing people's...
Stumbled across this a little while ago, published during the consultation period for the Interim Delivery Plan Sept 2023 A revitalized...
...bad science becomes orthodoxy: Reflections from a decade of debunking the PACE trial"...
...science becomes orthodoxy: Reflections from a decade of debunking the PACE trial". https://www.thereforme.uk/p/when-bad-science-becomes-orthodoxy
...Sepulveda The author notes multiple statistical issues in the PACE trial such as not accounting for multiple pairwise comparisons and...
Seems like you have an excellent grasp of all the main issues . If you take this on you will have to be very firm with the students about how much...
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