It would be very worrying to suggest trials of bedbound patients without mentioning the ethics given a big problem with bps is many of those...
...this can be used incorrectly against patients, as it was in the PACE trial. However that isn't a reason for just rejecting the science, as that...
A Digital Platform with Activity Tracking for Energy Management Support for Long Covid: A Randomized Control Trial
The SF36 is very susceptible to priming i.e. a change in your frame of reference for people with ME/CFS. I think Graham's excellent video about...
PACE also reported improvement with 6MWT after 6mo. Apart from various issues that experts raised with the data, 6 mo was just not long enough...
...COPD. I don't think this would have been true for most of the PACE trial participants, provided they weren't in PEM. And, I don't think the...
Compatible with bias. The result was what you would expect from a trial open to major bias from subjective outcome measures on the basis of an...
I have lost you there. PACE essentially showed a minimal difference between treatment arms compatible with bias. How does that tells anything at...
...and unfairly panning studies before even looking at them. The PACE trial is an interesting example. Clearly many patients (bedbound) are...
There are actually lots of clinical trials of this, easily hundreds (CBT is very much the same idea). Not controlled, because it's not feasible....
Agree with all of you points and adding this; there were no actometers right or were not used? So the distance was self-reported and participants...
I don't remember doing so, but as this was yesterday morning there is no chance I would recall :) Possibly - but a small difference vs none isn't...
...group, like anti vaxxers and climate change deniers. The PACE trial itself demonstrated that the ideas it was based on, deconditioning in the...
...how maliciously anti-scientific patients were to criticise his PACE trial. I was shocked not just that a medic should produce such a...
Wilshire et al. reanalysed the PACE trial using the original protocol, and (unsurprisingly) got different results. I didn't see anywhere in their...
...So, if a fitness test showed no improvement, but the PACE trial 6 minute walking test showed small improvements in all the treatment arms, with...
Did it though? Here are the PACE trial results Group: Baseline distance (m): 52 week distance (m) Adaptive Pacing: 314: 334 CBT: 333: 354 GET:...
29 is this: https://www.s4me.info/threads/the-long-covid-19-wearable-device-study-scripps-translational-science-institute-california.36078/
...this group’s severity compares with people who took part in the Pace trial? The six minute walking test worked perfectly well there to expose...
100% true this is one of the things people criticised the PACE trial for. I still look forward to their final results but view them with a...
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