Widely reported mostly by themselves. Have they reached a dead end with this finding in ME and are now just moving on to new diseases? What next...
...from ME/CFS patients, the Transient Receptor Potential Melastatin 3 (TRPM3) ion channel. NK cells from 6 healthy controls (HC) and 6 GWI...
...doing small, possibly flawed, studies based on the foundation of the TRPM3 finding without proving beyond all doubt that there is a real...
But perhaps this study can be used to justify a more rigorous replication study to explore this TRPM3 idea as a key lab-based diagnostic marker?
...Frontiers in Immunology Investigation into the restoration of TRPM3 ion channel activity in post-COVID-19 condition: a potential...
...and pain-sensitive Transient Receptor Potential Melastatin 3 and 8 (TRPM3 and TRPM8) ion channels are functionally associated in the lipid...
Full title: Investigation into the restoration of TRPM3 ion channel activity in post COVID-19 condition: a potential pharmacotherapeutic target...
Thread on the research on LDN in vitro Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells of...
article in Ausdoc A key to a ‘faulty’ lock: Why Aussie researchers are excited about naltrexone for CFS...
...and sex-matched HCs. The outcomes reported here potentially reflect TRPM3 dysfunction identified in this condition suggesting that ME/CFS is a...
...and framing, these mean little. The researchers found that the TRPM3 ion channels in the 9 patients were functioning like the TRPM3 ion...
...proteins known as transient receptor potential melastatin 3 (TRPM3) ion channels in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)...
...preliminary research. And so what if people with ME/CFS have fewer TRPM3 receptors on the natural killer cells and neuroinflammation? There...
...and ME/CFS patients" by Sasso, Marshall-Gradisnik et al Measured TRPM3 ion channel activity in isolated NK cells from 5 people each with...
My bolding This group of researchers are the only ones to have found this association and have been pushing it for at least five years now.
...channel function, namely Transient Receptor Potential Melastatin 3 (TRPM3). Long-term effects of severe acute respiratory syndrome coronavirus...
...presentation was titled Effect of IL2 stimulation and treatment of TRPM3 ion channels: co-localisation with PIP2 and NK cell function in ME/CFS...
Thats my concern as well. NCNED claim that TRPM3 dysfunction is the cause of ME/CFS, and that naltrexone repairs it, but we know that anecdotally...
...Research Journal of Translational Medicine "Impaired TRPM3-dependent calcium influx and restoration using Naltrexone in natural killer cells...
...Cations include sodium, potassium, magnesium, calcium and others. TRPM3 is most prominently expressed in the kidney with lower expression...
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