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ABSTRACT Introduction We aimed to assess the cost-effectiveness of non-pharmacological interventions for fatigue in patients with chronic conditions in the UK. Methods This systematic review of cost-effectiveness studies aligns with the Preferred Reporting Items for Systematic Reviews and...

ABSTRACT Introduction: Though there has been much discussion about post-acute sequelae of SARS-CoV-2 infection, there has been limited study on symptoms following infection with other respiratory viruses. Methods: In this retrospective chart review, we reviewed the medical records of 92...

Letter received via email sent to all members of the 'Task and Finish Group' from Ashley Dalton MP, Parliamentary Under-Secretary of State for Public Health and Prevention Letter also attached as Word document.

When my capacity allowed I attended a number of these meetings as a patient rep from DecodeME. Unfortunately it became obvious very rapidly it was a complete waste of my energy and time and unfortunately my assessment seems to have been proven correct.

That is the back-up plan assuming that we can't find a better solution. And yes, contact details are stored to enable recontacting when appropriate.

Continuity. It would need somewhere where the data can be stored, and people to process any application and distribute the data. At the moment it is stored on servers at the University of Edinburgh, there is a data access committee to review applications, and UoE staff who can process successful...

Abstract Background Individuals with prolonged symptoms after a mild traumatic brain injury (mTBI) report requiring more effort to complete complex and sustained activities. However, the relationship between cognitive workload and patient-reported symptoms is unclear. Objective To compare the...

Highlights • Functional cognitive disorder can occur comorbidly with Alzheimer's disease. • Clinical clues may identify patients at risk of converting to Alzheimer's disease. • This study has implications for management, prognosis and research trials. • We propose potential mechanisms which may...

Abstract Background Deficits in emotional awareness may contribute to the development and maintenance of somatic symptoms. This study explored emotional awareness deficits and their association with somatic symptoms among individuals with a high somatic symptom burden from an online community...

Yes.

Abstract Epstein-Barr Virus (EBV) is an endemic herpesvirus implicated in autoimmunity, cancer, and neurological disorders. Though primary infection typically resolves with subclinical symptoms, long-term complications can arise due to immune dysregulation or viral latency, in which EBV DNA is...

Highlights • Individuals with fibromyalgia require higher incentives for physical effort tasks. • No differences in cognitive effort task between fibromyalgia and control groups. • Fibromyalgia participants display increased willingness to wait for rewards. • This suggests higher...

"Our findings reveal that the most frequently reported psychosomatic symptoms are fatigue, back pain, a bloated stomach, and headaches. These physical symptoms often lie at the intersection of psychological and somatic factors, which largely accounts for the manifestation of psychosomatization...

"In essence, fatigue, back pain, a bloated stomach, and headaches appear to be psychosomatic symptoms that frequently manifest, often in combination. This suggests that special attention should be paid to such symptom clusters during differential diagnosis, since, as Wise (1) explains...

The primary objective of this study was to examine the relationship between personal variables, as measured by the NEO-PI-R, and psychosomatic symptoms, assessed through the PSS, from a neuropsychological perspective. The secondary aim was to evaluate the frequency of various psychosomatic...

"A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases. These include: asthma chronic obstructive pulmonary disorder inflammatory bowel disease Chronic inflammation-related diseases have been...

Abstract Objectives To evaluate the frequency and number of vulnerability factors for the development of pain-predominant disorders of gut–brain interaction (p-DGBI) in a well-defined cohort of pediatric patients and examine associations with pain severity and functional impairment. Methods...

Full title: Myasthenia gravis with antibodies against the AChR, current knowledge on pathophysiology and an update on treatment strategies with special focus on targeting plasma cells Highlights • Thymic involution, follicular hyperplasia and thymoma observed in AChR-MG are associated with...

Highlights The BDS checklist score was negatively associated with autonomic arousal. Individuals with FSD, especially multi-organ, had faster heart rates, independent of sex, age, smoking, and activity. An increased sympathetic neural and neurohormonal activity in patients with FSD may be...

Abstract Objectives: Fatigue is the main symptom of primary biliary cholangitis (PBC), but has not yet been improved by any therapeutic intervention. This study evaluated the efficacy and safety of hypnosis and psychoeducation in improving fatigue associated with PBC (PBC-HOPE ClinicalTrial.gov...