Search results for query: cox17

COX17 was one of the 259 core genes identified in this study. COX17 protein levels were also decreased in ME/CFS muscle tissue in the WASF3 study: WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome, 2023 Hwang et...

Comma separated list of the 259 candidate core genes. Nice to see ABCA1 and ABCC6 : Related to ABCA1 and ABCC6 we have the following: ABCC6 https://www.s4me.info/threads/abcc6-and-pathogenic-snps.14251/#post-246766 and ABCA1...

...In the WASF3 paper they found the following: WASF3 higher in ME/CFS PERK higher in ME/CFS BiP (GRP78) lower in ME/CFS CIV subunits (MTCO1 and COX17) lower in ME/CFS, respectively showed a significant negative correlation with that of both WASF3 and PERK (When human myoblasts were put under...

...and effect sizes (cohen's D): Gene: WASF3 P-value: 0.0859249 Cohen's d: 0.7596534 Gene: MTCO1 P-value: 0.0007785032 Cohen's d: 2.143763 Gene: COX17 P-value: 0.00237593 Cohen's d: 1.633564 Gene: PERK P-value: 0.02902655 Cohen's d: 0.9279234 Gene: BiP P-value: 0.004006675 Cohen's d...

...and 14 ME/CFS patients (from the intramural study i think so should be diagnosed well) and done western blots on them for WASF3, MTCO1, COX17, PERK and BiP. Here's the rest of the figure showing the western blots themselves and the quantified bar plots (just quantifying how large the blobs...