Understood. I find the Simmaron report in their ATG13 studies of "impaired ATG13-dependent autophagy, caused the infiltration of inflammatory M1...
Am I reading the Hanson/Grimson lab study right that they performed a differential gene analysis following provocation after an exercise...
There are two things I can think off as an armchair enthusiast. 1. The Selin lab has reported increased CD4+CD8+ T-cells in females (fresh blood,...
There was a zoom today hosted by Solve ME with presenters Dr Lisa Selin from UMass and Dr Kumar from Hifibio. Dr Selin stated that she was the...
Government funding and expansion of the ME/CFS Biobank seems like a no brainer ask for establishing a research network in the UK. It has a very...
Here is some data from the text.
I think reduced cerebral blood flow whether by brain scans (SPECT) or more recent modern methods has been replicated many times. I'd love to see...
I don't know if this thread is the right place or not but @paulendat mentioned that ACOD1/IRG1/Itaconate is highly expressed in microglial cells....
Did you watch the 2023 video from the NIH webcast (post about it)? Testing results showed no difference in Interferon-alpha (at 1 hr 10 mins) but...
For those that have data a person with ME/CFS has provided a genetic panel screening tool called GenVue which has been around since 2012 (old name...
For doctors there is a screening panel they can order. You need the specialist to choose the right selection of panels in case it is not the...
I guess one question I have from having looked at public cell expression databases, IRG1/ACOD1 is also highly expressed in Monocyctes. We know...
I enjoiyed the talk, however most of the talk was above my understanding. The key part for us thinking about PEM seems to be that Itaconate has a...
To clarify this for those that are not aware, from what I remember from having watched the videos a year or two ago, the itaconate shunt...
One thing I was surprised NOT to read about. Having ME/CFS clinics tied to research. If my reading of @Jonathan Edwards posts about his ground...
In Robert Phair's Itaconate shunt webinar he stated that IFN-alpha measurements are often several orders of magnitude off. This paper has...
I understand that there can be doubt when a skin biopsy shows you are in the 4th percentile of the population. There must be variation sample to...
I'm interested in a Janet and John story about p-values and what they really mean. Is 0.05 completely arbitrary? Where did the 0.05 come from....
From my understanding of Robert Phairs technical description the innate immune system can affect CAD via interferon-alpha/JAK pathway and that...
Talk by Mark Davis on the rare CD4 T cell type is here starting at 4hrs 48mins https://videocast.nih.gov/watch=42563 He talks about classical...
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