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Use of Common Drugs with Depression as Side Effect Increasing

Discussion in 'Health News and Research unrelated to ME/CFS' started by MeSci, Jun 13, 2018.

  1. MeSci

    MeSci Senior Member (Voting Rights)

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    from Physician's First Watch June 13, 2018

    Use of Common Drugs with Depression as Side Effect Increasing

    By Kelly Young

    Edited by
    - Lorenzo Di Francesco, MD, FACP, FHM

    Use of common drugs with depression as a possible side effect is increasing -- and the more of these drugs patients take, the greater their likelihood for depression -- a JAMA study finds.

    Researchers used data from 26,000 adults who participated in the National Health and Nutrition Examination Survey between 2005 and 2014. Roughly 37% said that within the past 30 days, they had used at least one medication that listed depression as a possible side effect (for example, proton pump inhibitors). That proportion increased over time.

    The prevalence of depression was 5% for people who didn't take any of these drugs, 7% for those taking one of these drugs, and 15% for those taking three or more. Strikingly, the depression prevalence was 61% among those co-prescribed gabapentin and cyclobenzaprine.

    The authors note: "The results suggest that physicians should consider discussing these associations with their patients who are prescribed medications that have depression as a potential adverse effect."

    Link(s):
    JAMA article (Free abstract) http://response.jwatch.org/t?ctl=377A0:5FF9B588B7CB016C4839A525CA813037D2B71D9A95FA21D3&

    Background: NEJM Journal Watch Psychiatry coverage of suicidality and antiepileptic drugs (Your NEJM Journal Watch registration required) http://response.jwatch.org/t?ctl=377A1:5FF9B588B7CB016C4839A525CA813037D2B71D9A95FA21D3&
     

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