The gut microbiome regulates host glucose homeostasis via peripheral serotonin, 2019, Martin et al

In mice.

Open access at https://www.pnas.org/content/early/2019/09/10/1909311116

 

Very interesting . Just had GI map test done which is flagging up some issues in gut.
Eta
Interestingly estrogen is being flagged up which shares/ influences seratonin signalling.

 

i had problems with hypoglycaemia for years. it was very frustrating as it cut in when i felt able to do something. Well enough to take the kids for school clothes, yay but by ten to twelve I hardly knew where i was. I was assured this was anxiety but I am now diabetic (which I think is related myself) and now I have a machine which shows my blood sugar really is low when I fell the way I did then.

Workwell says this is part of the problems of homeostatsis we have and with watching how my blood sugars go now I realise that my liver is slow to release glucose when I need it.

Anyway, we had a local doctor who said that ME was made worse by problems with REM sleep and that can be helped by prozac. I was at the try anything stage, this was in the 90s so I got it from my GP. It did nothing for my ME, surprise.

But... it helped the hypos! Strangely, I would manage that half an hour so i could have lunch at a decent time but when i did feel it I became bad very quickly, it was like it masked the symptoms but when it stopped i was where i would have been at that time.

My GP told me I had a phobia (of 12 o'clock???) and the prozac was making me less anxious as there was not possible biological reason for it to help hypoglycaemia (which she did not believe i had anyway)

Now it is all making sense, oh and the highish blood sugars of diabetes mean I do not have the same problem, though not going out much probably helps too!