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Special Issue: Recent Advances in Faecal Microbiota Transplantation, 2021, Review article and call for submissions.

Discussion in 'BioMedical ME/CFS News' started by Sly Saint, Jan 17, 2021.

  1. Sly Saint

    Sly Saint Senior Member (Voting Rights)

    Messages:
    6,804
    Location:
    UK
    Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain
    Hao-Ming Xu,1 Hong-Li Huang,1 You-Lian Zhou,1 Hai-Lan Zhao,1 Jing Xu,1 Di-Wen Shou,1 Yan-Di Liu,1 Yong-Jian Zhou,1 and Yu-Qiang Nie



    https://www.hindawi.com/journals/grp/2021/6699268/
     
    sebaaa, hinterland, Perrier and 5 others like this.
  2. MeSci

    MeSci Senior Member (Voting Rights)

    Messages:
    3,256
    Location:
    Cornwall, UK
    Disappointingly,

    "However, there are several limitations of using FMT in treating neurological, mental, and psychological diseases: (1) for many diseases, the therapeutic effects of FMT are limited to animal models and isolated cases."

    "Despite the promising results, the rationale for the clinical application of FMT is currently based on animal models and a few case reports and clinical studies. Large-scale randomized double-blind controlled trials are still needed to clarify the role of FMT in neurological diseases. At present, 33 clinical trials are ongoing on the potential therapeutic effects of FMT on mental and nervous system diseases (Table 3). Furthermore, the modes of delivering fecal microbiota also need to be improved. While a capsular form is more comfortable for the patients, fecal bacterial liquid in the form of washed/selective microbiota transplantation [188, 189] may be more effective in reducing the potential side effects."
     
    cfsandmore, sebaaa, Michelle and 2 others like this.

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