On Professor Maureen Hanson´s research, a Simmaron report

Helen · Dec 16, 2017

http://simmaronresearch.com/2017/12/simmaron-patient-day-summary-part-ii-hanson-report/

"Maureen Hanson has been making waves. An ace molecular plant biologist prior to entering the chronic fatigue syndrome (ME/CFS) field, Hanson has worked on mitochondrial and gene studies in plants dating back decades. Now, with her son ill from ME/CFS, she’s turned her talents to this field, and has made a difference in a hurry....."

The article presents her ongoing research, also with a background, and what is to come.

strategist · Dec 16, 2017

This is how lower respiratory capacity, mentioned in the article, was interpreted in a previous study:

Significantly altered mitochondrial stress test parameters in the CFS group compared with the healthy control group (Fig 3 & Fig 5) suggests that CFS patients may have systemic abnormalities in energy transduction, particularly when isolated PBMCs are put under mitochondrial stress. Lower reserve capacity observed in CFS patients are indicative of the cells of patients performing closer to their capacity in normal conditions without stress than healthy controls. Lowered maximal respiration suggests that the PBMCs of CFS patients are not capable of the same levels of respiration as healthy controls. Results showed that CFS patients can only increase their respiratory capacity 47% (±37%) from baseline when maximally stimulated by FCCP, which is significantly (p<0.001) lower than the 98% (±32%) increase in respiratory capacity achieved by control PBMCs. The consistently lower maximal respiration in the CFS cohort shows the inability of CFS patients to respire to the same extent as the control cohort when cellular stress is applied. The lower reserve capacity suggests that when CFS PBMCs come under stress they are less able to increase their respiration rate to compensate for the increase in stress leaving patients unable to fulfil cellular energy demands. Similar abnormalities in reserve capacity are thought to contribute to a range of other disease pathologies such as heart disease [49], neurodegenerative diseases in aging [50], and smooth muscle cell death [51].
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186802

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On Professor Maureen Hanson´s research, a Simmaron report

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On Professor Maureen Hanson´s research, a Simmaron report

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