Discussion in 'Health News and Research unrelated to ME/CFS' started by Sly Saint, Jan 11, 2020.
I know dr Phair has some theories on Trypyophan being a contributor to the IDO metabolic trap. But what are they referring to here?
From the Discussion:
The authors are suggesting fatigue after cancer treatment is different to CFS/ME:
Re the Trp levels:
So lymphoma survivors with fatigue and people with CFS/ME had similar levels of Trp (averages 73.4 and 73.4). And lymphoma survivors without fatigue and healthy controls from the CFS/ME study both had higher levels (77.6 and 77.8).
But here's the graph of Trp levels from this study of cancer survivors (Trp is the graph on the left):
Look at the huge amount of overlap (and note the truncated scale). If there's really a difference in average Trp levels between cancer survivors with and without fatigue, it's certainly not a consistent difference at the patient level.
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