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Medscape article: Low-Dose Naltrexone: An Inexpensive Medicine for Many Ills?

Discussion in 'BioMedical ME/CFS News' started by ahimsa, Mar 13, 2020.

  1. ahimsa

    ahimsa Senior Member (Voting Rights)

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    Article by Miriam Tucker - Low-Dose Naltrexone: An Inexpensive Medicine for Many Ills?

    https://www.medscape.com/viewarticle/926611

    (to read article I think you must register with Medscape)

     
    Yessica, MEMarge, Kalliope and 9 others like this.
  2. Caesar

    Caesar Senior Member (Voting Rights)

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    This is good news. Or is it?

    We hear a lot of LDN and ME/CFS through articles and case reports. How promising the meds is, and about it's benefits.
    But we need a big clinical trial on LDN! To proof it. If not, these articles gives no new info. As any other articles about probable meds who can be good for ME/CFS patients. For example, no way my doctor will subscribe LDN to me as things are now, no matter what these articles conveys. I wouldn't try it either, because the facts are largely missing.

    That said, I have heard a couple other patients have tried it, with success. Maybe this is something! I do not have access to Medscape, so I couldn't read the whole thing. And maybe I have missed something (I'm not an expert on LDN-studies). But do you know if there will be clinical trials on LDN and ME/CFS? I really hope so!
     
  3. Sly Saint

    Sly Saint Senior Member (Voting Rights)

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    https://www.s4me.info/threads/low-d...me-bolton-chapman-van-marwijk-jan-2020.13137/
    https://www.s4me.info/threads/low-d...atigue-syndrome-me-cfs-2019-polo-et-al.12426/
    https://www.s4me.info/threads/naltr...rom-me-cfs-patients-cabanas-et-al-2019.11797/
     
  4. Sly Saint

    Sly Saint Senior Member (Voting Rights)

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    don't know if this is any good or not

    Valarie from the United States shares her Chronic Fatigue Syndrome (CFS/ME) & Low Dose Naltrexone (LDN) Story
    https://ldnresearchtrust.org/valari...-syndrome-cfsme-low-dose-naltrexone-ldn-story
     
    MEMarge likes this.
  5. Creekside

    Creekside Senior Member (Voting Rights)

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    When I asked for some to try, my doctor was fine with prescribing it, because it's at such a low dosage that the chance of bad side effects was negligible. It worked extremely well for me, blocking my neuropathic pains, but didn't affect any other ME symptoms. After a year or two on LDN, I no longer needed it because the neuropathic pains had stopped. The minimum effective dose I worked out for me was 2.5 mg sublingually (needed ~1/3 less that way) alternated mornings and evenings every second day. At such a low dosage, any unnoticed side-effects from it would have been dwarfed by the health benefits of the exercise I was able to do without the pain. LDN sure improved my quality of life.
     
    Amw66, ukxmrv, MEMarge and 3 others like this.
  6. darrellpf

    darrellpf Established Member

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    I tried NDL for several months. For many years I've had a foreearm itch that was not relieved by any medication. LDN seeemed to fix that. One the other hand, it seemed to leave me with a numbness. Eventually I just stopped taking it. For me, it is one of many medications that provides a temporary enhancement of functionality but only serves to wear one down in the longer term.
     
    Milo likes this.
  7. DigitalDrifter

    DigitalDrifter Senior Member (Voting Rights)

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    I tried LDN back in 2015 and it didn't do anything for me.
     

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