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Cognitive decline and brainstem hypometabolism in long COVID: A case series, 2022, Jacques Hugon et al

Discussion in 'Other health news and research' started by Mij, Mar 17, 2022.

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  1. Mij

    Mij Senior Member (Voting Rights)

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    Abstract

    Objective
    To assess FDG cerebral PET in patients suffering from cognitive impairment linked to Long COVID. The COVID pandemic has affected dozens of millions of people around the world and has resulted in the deaths of more than 3 million people. Following the acute forms, it has been reported sometimes long forms of COVID, with involvements of several organs including the brain. Neurological complications can include cognitive disturbances (brain fog) that are very common and can seriously disturb the life of patients.

    Methods
    Fluorodeoxyglucose PETs were performed in 3 patients with cognitive decline following COVID infection.

    Results
    We report here 3 cases of brain fog with major hypometabolic areas of the pons revealed by the cerebral FDG PET.

    Conclusion
    The dysfunction of the locus coeruleus in these patients could partly explain the cognitive disorders observed. Further studies involving larger cohorts of patients suffering from cognitive dysfunction will be needed to determine if the brainstem is frequently affected in these patients.

    https://onlinelibrary.wiley.com/doi/10.1002/brb3.2513
     

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