I found it interesting that the affected genes in the study (ALAD and p16) are involved in red blood cell development and some cancers. Lead poisoning could reduce gene expression in humans Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning. https://www.global.hokudai.ac.jp/blog/lead-poisoning-could-reduce-gene-expression-in-humans/ Original study: Yared B. Yohannes, et al. Blood Lead Levels and Aberrant DNA Methylation of the ALAD and P16 Gene Promoters in Children Exposed to Environmental-Lead. Environmental Research. https://doi.org/10.1016/j.envres.2020.109759 June 05, 2020. DOI: 10.1016/j.envres.2020.109759.