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Blood Lead Levels and Aberrant DNA Methylation of the ALAD and P16 Gene Promoters in Children Exposed to Environmental Lead, 2020, Yohannes, et al.

Discussion in 'Other health news and research' started by Webdog, Aug 8, 2020.

  1. Webdog

    Webdog Senior Member (Voting Rights)

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    I found it interesting that the affected genes in the study (ALAD and p16) are involved in red blood cell development and some cancers.

    Lead poisoning could reduce gene expression in humans
    Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning.
    https://www.global.hokudai.ac.jp/blog/lead-poisoning-could-reduce-gene-expression-in-humans/
    [​IMG]

    Original study:
    Yared B. Yohannes, et al. Blood Lead Levels and Aberrant DNA Methylation of the ALAD and P16 Gene Promoters in Children Exposed to Environmental-Lead. Environmental Research.
    https://doi.org/10.1016/j.envres.2020.109759
    June 05, 2020.
    DOI: 10.1016/j.envres.2020.109759.
     
    Amw66, Yessica, alktipping and 2 others like this.

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