Once again on B12 / folate... When I browse the symptoms of B12 and/or folate deficiency I see things I have suffered with for years. Tinnitus, palpatations, tongue inflammation, etc. Now I know these overlap with ME symptoms, but I want to try supplementation and see if there is any effect. Before visiting these forums I had no idea what a complex subject this was, and I am still not clesr what the best option is for me RE supplementation. I have had serum folate and B12 tests in the past. The B12 was in the upper range, and folate towards the lower suggested range. Last spring I had a month on high strength sublingual B12. I felt like it was perhaps one of the only times I'd felt some noticable change from supplementation. However, around that time some visual problems that had started up seemed to get worse - for example I got black floaters. I wasn't sure if this was related to the methycobalamin. If I was try supplementation again, I am wondering: What are your experiences with B12 and folate supplementation? Has anyone had any problems or benefits taking the two together? Thanks! Note. I have not had any genetic testing to check for gene mutations etc.