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  1. Simon M
    Post

    No signs of neuroinflammation in women with [CFS] or Q fever fatigue syndrome using the TSPO ligand [11C]-PK11195, 2021, Raijmakers, Knoop et al

    What does this tell us? Hold on there! This is a second study with n=9 and using an old-generation "noisy" tracer as a proxy of inflammation. We...
    Post by: Simon M, Apr 13, 2021 in forum: BioMedical ME/CFS Research
  2. Simon M
    Post

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    I think this is the central journalistic flaw and why it was a fundamentally biased piece. Of course, case studies and interviews are a really...
    Post by: Simon M, Apr 9, 2021 in forum: Epidemics (including Covid-19)
  3. Simon M
    Post

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    Merged thread. Ten minute segment on Newnight looking at the 'controversy' over how to treat LC and ME/CFS, but isn't very balanced and gives the...
    Post by: Simon M, Apr 9, 2021 in forum: Epidemics (including Covid-19)
  4. Simon M
    Post

    Long Covid epidemiology (prevalence, incidence, recovery rates)

    How many have long covid? And how many have something with symptoms as severe as mecfs? Yes, seems to be a lot less than you'd expect for...
    Post by: Simon M, Apr 6, 2021 in forum: Epidemics (including Covid-19)
  5. Simon M
    Post

    Long Covid epidemiology (prevalence, incidence, recovery rates)

    The ONS survey asked about impact on daily activities: no impact, limited a little or limited a lot. Only one in five of the 14% of people who...
    Post by: Simon M, Apr 1, 2021 in forum: Epidemics (including Covid-19)
  6. Simon M
    Post

    United Kingdom: Action for ME (AfME) news

    worth bearing in mind that Action for ME is a partner in the DecodeME study its chief executive, Sonya Chowdhury, is chair of the study's...
    Post by: Simon M, Mar 25, 2021 in forum: News from Organisations
  7. Simon M
    Post

    COVID-19 Survivors' Reports of the Timing, Duration, and Health Impacts of Post-Acute Sequelae of SARS-CoV-2 (PASC) Infection, 2021, Lambert et al

    Very interesting difference in sex ratio between hospitalised and non-hospitalised cases: — hospitalised: 41% women. — Non-hospitalised: 86%...
    Post by: Simon M, Mar 24, 2021 in forum: Epidemics (including Covid-19)
  8. Simon M
    Thread

    Participation bias

    Split from The course of the illness for ME patients in Norway, 2021, Schei and Angelsen The potential effect of sample biases on DecodeME...
    Thread by: Simon M, Mar 15, 2021, 2 replies, in forum: Health News and Research unrelated to ME/CFS
  9. Simon M
    Post

    The course of the illness for ME patients in Norway, 2021, Schei and Angelsen

    looking at the graph, it's 2015 before we could be confident there is a decline, rather than simply a plateau, and the survey was done in 2019....
    Post by: Simon M, Mar 15, 2021 in forum: BioMedical ME/CFS Research
  10. Simon M
    Post

    Clinical and epidemiological data of COVID-19 from Regensburg, Germany: a retrospective analysis of 1084 consecutive cases, 2021, Lampl et al

    Long covid estimate of 9% max assuming I have understood the method right, this was a fairly comprehensive and unbiased original sample. Which...
    Post by: Simon M, Mar 15, 2021 in forum: Epidemics (including Covid-19)
  11. Simon M
    Post

    The course of the illness for ME patients in Norway, 2021, Schei and Angelsen

    Thanks to everyone who contributed to the discussion. This is my attempt to summarise the main points about possible explanations for the...
    Post by: Simon M, Mar 12, 2021 in forum: BioMedical ME/CFS Research
  12. Simon M
    Post

    The course of the illness for ME patients in Norway, 2021, Schei and Angelsen

    I can think of a number of possible explanations as to why the study finds a steady increase in the onset of ME/CFS, since the mid-80s to around...
    Post by: Simon M, Mar 11, 2021 in forum: BioMedical ME/CFS Research
  13. Simon M
    Post

    The course of the illness for ME patients in Norway, 2021, Schei and Angelsen

    The remarkable onset graph - thoughts? The report includes a graph showing year of onset for 5800 people. This is a very large sample and the...
    Post by: Simon M, Mar 11, 2021 in forum: BioMedical ME/CFS Research
  14. Simon M
    Post

    Clinical Characteristics, Activity Levels and Mental Health Problems in Children with Long COVID: A Survey of 510 Children, 2021, Buonsenso et al

    This study might yet be consistent with ME/CFS. The average age in the study was 10.3 years. And a couple of studies for ME have shown that the...
    Post by: Simon M, Mar 10, 2021 in forum: Epidemics (including Covid-19)
  15. Simon M
    Post

    UK spends £18.5m on 4 long covid studies

    ME/CFS what I love to see is this applied to ME/CFS research. The obvious thing would be a cohort of glandular fever patients. I think there are 5...
    Post by: Simon M, Mar 4, 2021 in forum: Epidemics (including Covid-19)
  16. Simon M
    Thread

    UK spends £18.5m on 4 long covid studies

    £18.5 million awarded to new research projects to understand and treat long COVID The NIHR and UK Research and Innovation (UKRI - the MRC is...
    Thread by: Simon M, Mar 4, 2021, 4 replies, in forum: Epidemics (including Covid-19)
  17. Simon M
    Post

    Effects of Post-Exertional Malaise on Markers of Arterial Stiffness in Individuals with ME/CFS: Bond et al 2021

    given that the study made 24 comparisons and didn't seem to make any adjustments for multiple comparisons, the single "significant" P value of...
    Post by: Simon M, Mar 1, 2021 in forum: BioMedical ME/CFS Research
  18. Simon M
    Post

    British Medical Association article: Long Covid - we've been here before, 2021, J. Trueland

    my memory is rubbish, but weren't F and M looking at something like this at some point - or some researchers. Sorry to be so vague! I thought...
    Post by: Simon M, Feb 16, 2021 in forum: Epidemics (including Covid-19)
  19. Simon M
    Post

    A Molecular network approach reveals shared cellular and molecular signatures between CFS and other fatiguing illnesses, 2021, Comella et al

    Tiny study: To provide some insight into the molecular processes that underlie CFS, we carried out a study on 15 patients diagnosed with CFS and...
    Post by: Simon M, Feb 3, 2021 in forum: BioMedical ME/CFS Research
  20. Simon M
    Post

    The difficulties of conducting intervention trials for the treatment of [ME/CFS]: Expert testimony to NICE guidelines committee by Jonathan Edwards

    Allow me to speculate. Presumably, NICE undertook some kind of evidence review in 2007 and found the evidence (pre-PACE, even lower quality) for...
    Post by: Simon M, Jan 14, 2021 in forum: PsychoSocial ME/CFS Research
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